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TranscriptomicsTranscriptional profiling of EJC depletion by RNA-Seq using the SOLiD platform (Applied Biosystems)
Signaling pathways are controlled by a vast array of post-translational mechanisms. By contrast, little is known regarding the mechanisms that regulate the expression of their core components. We conducted an RNAi screen in Drosophila for factors modulating RAS/MAPK signaling and identified the Exon...
ORGANISM(S): Drosophila melanogaster 
2010-10-19 | E-GEOD-24012 | biostudies-arrayexpress
ProteomicsThe scaffold protein CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling
Cell motility is a critical feature of invasive tumour cells that is governed by complex signal transduction events. Particularly, the underlying mechanisms that bridge extracellular stimuli to the molecular machinery driving motility remain partially understood. Here, we show that the scaffold prot...
ORGANISM(S): Homo sapiens (Human) 
2023-04-20 | PXD038687 | Pride
Cancer cell motility Axl signaling Cnk2 
UnknownLong-term effectiveness of aripiprazole once monthly on functioning and quality of life in schizophrenia: results of year 2 of the ReLiAM study.
Not available
S-EPMC11562632 | biostudies-literature
ModelsCaron2010_mTORsignalingNetwork_ActivityFlow
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model ha...
2005-01-01 | MODEL1012220004 | BioModels
ModelsCaron2010_mTOR_SignalingNetwork
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model ha...
2005-01-01 | MODEL1012220002 | BioModels
ModelsCaron2010_mTORC1_UpstreamRegulators
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model ha...
2005-01-01 | MODEL1012220003 | BioModels
ProteomicsPosternak_PROTACagainstBRAFV600E_P124_Lumos
The files are associated with a manuscript submitted for publication by Ganna Posternak et al. The main goal of this paper was functionally characterize the mechanism of action of a PROTAC designed to target BRAFV600E.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-11-07 | MSV000084551 | MassIVE
ProteomicsPosternak_PROTACdegradation_P124_Lumos
The files are associated with a manuscript submitted for publication by Ganna Posternak et al. The main goal of this paper was functionally characterize the mechanism of action of a PROTAC designed to target BRAFV600E. This dataset provides a proteome-wide view of protein degradation after treatment...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-10 | MSV000085271 | MassIVE
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