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Traynard2016 - Mammalian cell cycle regulation - Logical Model This model is described in the article: Logical model specification aided by model-checking techniques: application to the mammalian cell cycle regulation. Traynard P, Fauré A, Fages F, Thieffry D. Bioinformati...
2016-11-29 | MODEL1611230001 | BioModels
Mbodj2016 - Mesoderm specification during Drosophila development This model is described in the article: Qualitative Dynamical Modelling Can Formally Explain Mesoderm Specification and Predict Novel Developmental Phenotypes. Mbodj A, Gustafson EH, Ciglar L, Junion G, Gonzale...
2016-10-25 | MODEL1607310000 | BioModels
Fig 3B from the following paper\r\nLogical modelling of Drosophila signalling pathways. Mbodj A, Junion G, Brun C, Furlong EE, Thieffry D. Mol Biosyst. 2013 Sep;9(9):2248-58. doi:10.1039/c3mb70187e
Attention: As this model cannot be encoded in SBML at this time, the SBML file contains the whole model in GINML , a different XML model description language, in its main annotation element. Still, the model can be loaded by GINsim as it is by just ignoring th...
2005-01-01 | MODEL0912180000 | BioModels
Chaouiya2013 - EGF and TNFalpha mediated signalling pathway This model is described in the article: SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools. Chaouiya C, Bérenguier D...
2024-09-02 | BIOMD0000000562 | BioModels
Using homogenous populations of cells undergoing lineage switching we studied enhancer nucleation. Examination of 3 histone marks several time points after induction of transdifferentiation
ORGANISM(S): Mus musculus 
Using homogenous populations of cells undergoing cell switching we observed an interplay between lymphoid and myeloid transcription factors during lineage switching Examination of transcription factors genome-wide binding profiles several time points after induction of B-cell to macrophage lineage s...
ORGANISM(S): Mus musculus 
The Mitogen-Activated Protein Kinase (MAPK) network consists of tightly interconnected signalling pathways involved in diverse cellular processes, such as cell cycle, survival, apoptosis and differentiation. Although several studies reported the involvement of these signalling cascades in cancer der...
Motivation: To understand the behaviour of complex biological regulatory networks, a proper integration of molecular data into a full-fledge formal dynamical model is ultimately required. As most available data on regulatory interactions are qualitative, logical modelling offers an interesting frame...
Cytokines such as TNF and FASL can trigger death or survival depending on cell lines and cellular conditions. The mechanistic details of how a cell chooses among these cell fates are still unclear. The understanding of these processes is important since they are altered in many diseases, including c...
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