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Transcriptional profiling of lung in mice exposed to cigarette smoke and poly(I:C) and treated or not with Thioredoxin-1 Total RNA samples were pooled from 3 murine lungs for each experimental group.
ORGANISM(S): Mus musculus 
Thioredoxin Reductase 1 (isoform 4) was incubated with aspirin for 1 hour at 37 C followed by SDS PAGE. Samples were picked from SDS PAGE gel, digested with trypsin, and sent for LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027882 | Pride
Genetic disruption of thioredoxin reductase 1 protects against acetaminophen (APAP) toxicity. To determine the role of the thioredoxin system on xenobiotic metabolism we challeneged wildtype and txnrd1liver-null mice with acetaminophen. Adult male wildtype and txnrd1 liver-null mice (C57BL6/J) were ...
ORGANISM(S): Mus musculus 
Oxidized thioredoxin-1 restrains the NLRP1 inflammasome [NTERT-1]
Oxidized thioredoxin-1 restrains the NLRP1 inflammasome [mBMDM]
Inhibition of thioredoxin reductase 1 sensitizes glucose-starved glioblastoma cells to disulfidptosis 1
Oxidized thioredoxin-1 restrains the NLRP1 inflammasome.
Thioredoxin-1 promotes the restoration of alveolar bone in periodontitis with diabetes
This experiment was to determine if we could observe changes in gene expression following the attenuation of one of the primary redox regulators of cells - thioredoxin reductase 1. The experiment was set up with two cell lines that expressed different basal levels of TR1. LOX cells represent an aggr...
ORGANISM(S): Homo sapiens 
Genetic disruption of thioredoxin reductase 1 protects against acetaminophen (APAP) toxicity. To determine the role of the thioredoxin system on xenobiotic metabolism we challeneged wildtype and txnrd1liver-null mice with acetaminophen.
ORGANISM(S): Mus musculus 
2013-06-08 | GSE37874 | GEO
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