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F-ALDH is a recently characterized psychrophilic aldehyde dehydrogenase from Flavobacterium PL002. Thiram was shown to inhibit its enzymatic activity, yet the mechanism of inhibition is unknown. We have used low flow liquid chromatography (nanoLC) coupled to tandem mass spectrometry (MS/MS) to study...
ORGANISM(S): Flavobacterium sp. PL002 
2025-10-24 | PXD066425 | Pride
Purpose: To figure out the molecular function of disulfiram, thiram and CX-6258, RNA sequencing was performed to analyze the geome-wide change of disulfiram, thiram and CX-6258 treated HGC-27 cells compared to those of control DMSO treated cells. Methods: Total mRNA was extracted from HGC-27 cells. ...
ORGANISM(S): Homo sapiens 
2024-06-12 | GSE168618 | GEO
Genomics
thiram gut sample sequencing
Whole transcriptomes analyses of HGC-27 cell line treated with control DMSO, disulfiram, thiram or CX-6258
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