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ModelsBucher2011_Atorvastatin_Metabolism
This is the model of atorvastatin metabolism in hepaitc cells described in the article: A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes Joachim Bucher , Stephan Riedmaier , Anke Schnabel , Katrin Marcus , G...
2024-09-02 | BIOMD0000000328 | BioModels
TranscriptomicsTranscriptomics of Xanthomonas campestris pv campestris in cabbage xylem sap
Xylem sap of young cabbage plantlets was recovered from root pressure exudation and used as a growth medium for the vascular pathogen Xanthomonas campestris pv campestris, the causative agent of the black rot of Brassicaceae.
ORGANISM(S): Xanthomonas campestris pv campestris 
2014-01-04 | E-MTAB-2290 | biostudies-arrayexpress
UnknownHuman melanoma transcriptom is modulated by cold plasma treatment
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-65972 | biostudies-other
TranscriptomicsClassical Hodgkin lymphoma shows epigenetic features of an abortive plasma cellular differentiation: expression of A/T-treated vs. untreated B-cell lines
Background Epigenetic changes are involved in the extinction of the B-cell gene expression program of classical Hodgkin lymphoma. However, little is known regarding epigenetic similarities between classical Hodgkin lymphoma and plasma cell myeloma cells, both of which share an extinction of the gene...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-21252 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression profiling analysis of a Sphingomyelin Synthase 1 mutant mouse model
Lysosomal storage diseases are congenital lipid metabolism disorders, often accompaning by male infertility. Sms1, the enzyme, that generates sphingomyelin from ceramides seems to be involved in spermatogeneis and spermiogenesis. Therefore, testis but also muscle and brain of a mouse line carrying a...
ORGANISM(S): Mus musculus 
2013-01-01 | E-GEOD-37359 | biostudies-arrayexpress
TranscriptomicsHuman melanoma transcriptom is modulated by cold plasma treatment
Treatment of tumor progression and metastasis continues to be of major importance in the field of cancer. It is reported that cancer cells often show a pronounced sensitivity towards oxidative stress. Cold plasma offers the ability to deliver a delicate mix of reactive oxygen and nitrogen species di...
ORGANISM(S): Homo sapiens 
2015-02-18 | E-GEOD-65972 | biostudies-arrayexpress
TranscriptomicsLong-term exposure to cold plasma-generated ROS –an in vitro model for redox-related diseases of the skin
Oxidative stress illustrates an imbalance between radical formation and removal. Frequent redox stress is critically involved in a variety of human pathologies including cancer, psoriasis, and chronic wounds. However, reactive species pursue a dual role being involved in signaling on the one hand an...
ORGANISM(S): Homo sapiens 
2015-11-11 | E-GEOD-74876 | biostudies-arrayexpress
TranscriptomicsClassical Hodgkin lymphoma shows epigenetic features of an abortive plasma cellular differentiation: expression of PCM vs. B-cell lines
Background Epigenetic changes are involved in the extinction of the B-cell gene expression program of classical Hodgkin lymphoma. However, little is known regarding epigenetic similarities between classical Hodgkin lymphoma and plasma cell myeloma cells, both of which share an extinction of the gene...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-28079 | biostudies-arrayexpress
TranscriptomicsClassical Hodgkin lymphoma shows epigenetic features of an abortive plasma cellular differentiation: expression of Hodgkin vs. B-cell lines
Background Epigenetic changes are involved in the extinction of the B-cell gene expression program of classical Hodgkin lymphoma. However, little is known regarding epigenetic similarities between classical Hodgkin lymphoma and plasma cell myeloma cells, both of which share an extinction of the gene...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-21251 | biostudies-arrayexpress
TranscriptomicsTranscriptional co-factor TBLR1 controls lipid mobilization in white adipose tissue
Lipid mobilization (lipolysis) in white adipose tissue (WAT) critically controls lipid turnover and adiposity in humans. While the acute regulation of lipolysis has been studied in detail, the transcriptional determinants of WAT lipolytic activity remain still largely unexplored. Here we show that ...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-43658 | biostudies-arrayexpress
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