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UnknownMultistrain Probiotic Modulation of Intestinal Epithelial Cells' Immune Response to a Double-Stranded RNA Ligand, Poly (I:C)
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-54042 | biostudies-other
TranscriptomicsMultistrain Probiotic Modulation of Intestinal Epithelial Cells' Immune Response to a Double-Stranded RNA Ligand, Poly (I:C)
A commercially available product containing three probiotic bacterial strains (Lactobacillus helveticus R0052, Bifidobacterium longum subsp. infantis R0033, and Bifidobacterium bifidum R0071) was previously shown in animal trials to modulate both TH1 and TH2 immune responses. Clinical studies on thi...
ORGANISM(S): Homo sapiens 
2014-01-14 | E-GEOD-54042 | biostudies-arrayexpress
TranscriptomicsGenome-Wide Expression Profiling of Human Colonic Epithelial Cell Model Co-challenged with Single, Multi-strain Probiotics and Pro-inflammatory Stimulus, poly (I:C)
One of the key impacts of probiotic bacteria is the ability to beneficially modulate innate and adaptive immune responses of various cell types of the gut-associated lymphoid tissue. In this study we used an in vitro intestinal epithelial cell model to investigate the impact of three probiotic bacte...
ORGANISM(S): Homo sapiens 
2015-08-25 | E-GEOD-71515 | biostudies-arrayexpress
TranscriptomicsOncogenic MYC induces a dependency on the spliceosome in human cancer
c-MYC (MYC) overexpression or hyperactivation is one of the most common drivers of human cancer. Despite intensive study, the MYC oncogene remains recalcitrant to therapeutic inhibition. Like other classic oncogenes, hyperactivation of MYC leads to collateral stresses onto cancer cells, suggesting t...
ORGANISM(S): Homo sapiens 
2015-09-03 | E-GEOD-66182 | biostudies-arrayexpress
UnknownDoes aggressive surgery improve outcomes? Interaction between preoperative disease burden and complex surgery in patients with advanced-stage ovarian cancer: an analysis of GOG 182.
Not available
S-EPMC4348639 | biostudies-literature
UnknownPersistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: Three month analyses of the COV-BOOST trial.
Not available
S-EPMC8993491 | biostudies-literature
UnknownPersistence of immune responses after heterologous and homologous third COVID-19 vaccine dose schedules in the UK: eight-month analyses of the COV-BOOST trial.
Not available
S-EPMC10116128 | biostudies-literature
TranscriptomicsMyotonic dystrophy type 1 (DM1) leads to altered mRNA expression in heart tissue
Myotonic dystrophy type 1 (DM1) is a dominantly inherited disease that affects multiple organ systems. Cardiac dysfunction is the second leading cause of death in DM1. We quantified gene expression in heart tissue from a heart-specific DM1 mouse model (EpA960/MCM) which inducibly expresses human DMP...
ORGANISM(S): Mus musculus 
2014-01-24 | E-GEOD-48991 | biostudies-arrayexpress
UnknownMenAfriNet: A Network Supporting Case-Based Meningitis Surveillance and Vaccine Evaluation in the Meningitis Belt of Africa.
Not available
S-EPMC6853281 | biostudies-literature
UnknownCanadian College of Medical Geneticists: clinical practice advisory document - responsibility to recontact for reinterpretation of clinical genetic testing.
Not available
S-EPMC11672037 | biostudies-literature
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