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ProteomicsMetrologically traceable quantification of three apolipoprotein E isoforms in cerebrospinal fluid
Apolipoprotein E (apoE) is a 317-amino-acid long glycoprotein with three common isoforms (apoE2, apoE3, and apoE4) encoded by three apoE alleles (ε2, ε3, and ε4). These polymorphic forms arise from single amino acid substitutions with Cys and Arg interchanged at positions 112 and 158 (mature protein...
ORGANISM(S): Homo Sapiens 
PXD038803 | panorama
ProteomicsBlood and urine multi-omics analysis of the impact of e-vaping, smoking and cessation. From exposome to molecular responses
Cigarette smoking is a major cause of preventable morbidity and mortality. While quitting smoking is the best option, switching from cigarettes to non-combustible alternatives (NCAs) such as e-vapor products is a viable harm reduction approach for smokers who would otherwise continue to smoke. A key...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-01-26 | MSV000091157 | MassIVE
TranscriptomicsTranscription profiling of E. coli TG1/pBS(Kan)Synhox and pBS(Kan) ability to produce hydrogen
E. coli TG1 with pBS(Kan)Synhox can produce more hydrogen than TG1/pBS(Kan). To reveal the difference of metabolic activity (gene expression) between these strains in producing hydrogen, the differential gene expression analyses were performed. All samples cultured in complex medium with fructose ...
ORGANISM(S): Escherichia coli 
2008-06-14 | E-GEOD-5905 | biostudies-arrayexpress
TranscriptomicsE. coli BW25113 ompA mutant vs wild type biofilm and E. coli BW25113 ompA/pCA24N_ompA vs ompA/pCA24N suspension cells
This Series involves two studies: 1) The gene expression of E. coli K-12 BW25113 ompA mutant strain vs. wild type strain glasswool biofilm cells and E. coli K-12 BW25113 ompA mutant vs. wild type polystyrene biofilm cells. 2) The gene expression of E. coli BW25113 ompA/pCA24N_ompA vs. ompA/pCA24N su...
ORGANISM(S): Escherichia coli 
2010-11-03 | E-GEOD-14064 | biostudies-arrayexpress
TranscriptomicsResponse of Escherichia coli to acetate in presence of 100 mM methyl α-D-glucopyranoside
This experiment was performed to challenge E. coli response to acetate when its growth rate flux is reduced by 40% with 100 mM methyl α-D-glucopyranoside. Control without inhibition in the exact same conditions was already published on ArrayExpress database (accession number E-MTAB-9086) and could ...
ORGANISM(S): Escherichia coli K-12 
2022-09-23 | E-MTAB-11717 | biostudies-arrayexpress
TranscriptomicsCDH1 knockout in mice
Employing Cre/loxP technology, a mouse model of liver specific Cdh1 (E-cadherin) depletion was created (fl/fl | +/wt). Previously, the mice had already been compared to littermates with normal Ecadherin levels (fl/fl | wt/wt), using a broad range of laboratory methods (Serum parameters, long-term we...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-54234 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli K-12 mutant ycfR biofilm vs wild type 15 hr LB glu biofilm cells
E. coli K-12 BW25113 mutant strain ycfR expression in biofilm cells relative to E. coli wild-type strain expression in biofilm cells. All samples cultured in LB glu with glass wool Experiment Overall Design: Strains: E. coli K-12 BW25113 wild type and mutant ycfR Experiment Overall Design: Medium: ...
ORGANISM(S): Escherichia coli 
2008-06-14 | E-GEOD-5904 | biostudies-arrayexpress
TranscriptomicsIdentification of genes regulated by gadE in E. coli O157:H7
Integrating laterally acquired virulence genes into the backbone regulatory network is important for the pathogenesis of Escherichia coli O157:H7, which has captured many virulence genes through horizontal transfer during evolution. GadE is an essential transcriptional activator of glutamate decarbo...
ORGANISM(S): Escherichia coli 
2010-05-18 | E-GEOD-13132 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of environmental Escherichia coli isolates indicates highly conserved ecophysiology
Escherichia coli, the common inhabitant of the mammalian intestine, exhibits considerable intraspecies genomic variation, which has been suggested to reflect adaptation to different ecological niches. Also, regulatory trade-offs, e.g., between catabolic versatility and stress protection, are thought...
ORGANISM(S): Escherichia coli 
2006-12-04 | E-GEOD-6407 | biostudies-arrayexpress
TranscriptomicsResponse of Escherichia coli to acetate concentration during growth on glucose
E. coli MG1655 was grown on M9 minimal medium supplemented with 15mM glucose and either 0, 10, 50 or 100 mM acetate. Transcriptomic analysis from exponential growing cells was performed using Agilent microarray A-MEXP-2232. This work was done with the help of students during practicals. Consequentl...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2020-08-21 | E-MTAB-9086 | biostudies-arrayexpress
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