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UnknownFirst person – Tobias Beigl, Ine Kjosas and Emilie Seljeseth
Not available
S-EPMC7725594 | biostudies-literature
MetabolomicsThe pyruvate kinase, a metabolic sensor powering glycolysis, drives the metabolic control of DNA replication

BACKGROUND: In all living organisms, DNA replication is exquisitely regulated in a wide range of growth conditions to achieve timely and accurate genome duplication prior to cell division. Failures in this regulation cause DNA damage with potentially disastrous consequences ...

2022-04-19 | MTBLS4415 | MetaboLights
TranscriptomicsComparative genomic hybridization of human nasal NK/T-cell Lymphoma (8 tumor samples, 2 cell lines)
A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) | Human genome-wide CIT-aCGH-V6-4.4K : 8 NKTCL biopsies, 2 NKTCL cell lines. Biopsies and cell lines of NK/T-cell lymphoma, nasal-type (NKTCL) were subject to combine...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-TABM-791 | biostudies-arrayexpress
ProteomicsMultiomics analysis of Papillary thyroid cancers identifies BAIAP2L1-BRAF fusion and requirement of TRIM25, PDE5A and PKCdelta for tumorigenesis
Papillary thyroid carcinoma (PTC) is one of the most common forms of thyroid cancer with a cure rate of over 90% after surgery. However, aggressive forms may still occur, and personalized therapeutic strategies are increasingly required. We subjected patient materials from a cohort of patients whose...
ORGANISM(S): Homo Sapiens (human) 
2023-02-22 | PXD034229 | JPOST Repository
TranscriptomicsComparative genomic hybridization of 84 head and neck squamous cell carcinoma
A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) | Human genome-wide CIT-aCGH-V7-4.7K : 84 HNSCC | Submitter : Aurelien de Reynies | Project leader : Bohdan Wazylyk
ORGANISM(S): Homo sapiens 
2010-05-15 | E-TABM-995 | biostudies-arrayexpress
TranscriptomicsGenotyping by array of human head and neck squamous cell carcinoma.
A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) |Illumina 370K SNP chips (chromosome 11 subpart) : 80 HNSCC | Submitter : Aurelien de Reynies | Project leader : Bohdan Wazylyk
ORGANISM(S): Homo sapiens 
2010-05-15 | E-TABM-994 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human glioblastomas (56 tumor samples)
A ‘Cartes d’Identite des Tumeurs’ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | Affymetrix HG-U133 Plus 2.0 : 56 glioblastomas |Submitter : Aurelien de Reynies | Project leader : Francois Berger
ORGANISM(S): Homo sapiens 
2010-07-07 | E-TABM-898 | biostudies-arrayexpress
TranscriptomicsRNA-seq of livers from female mice treated for eight weeks with the glucagon analogue, NNC9204-0043, compared to female mice treated with PBS (control group)
Chronic glucagon receptor activation with a long-acting glucagon analogue increases amino acid catabolism, and to dissect the molecular mechanism underlying this effect, RNA sequencing of liver biopsies from female mice treated for eight weeks with GCGA or PBS were performed.
ORGANISM(S): Mus musculus 
2022-10-11 | E-MTAB-12040 | biostudies-arrayexpress
TranscriptomicsRNA-seq of livers from mice treated for eight weeks with the glucagon receptor antibody, REGN1193, compared to mice treated with a control antibody, REGN1945, (control group)
Chronic glucagon receptor inhibition with a glucagon receptor antibody decreases amino acid catabolism and ureagenesis, while increasing plasma triglyceride concentrations, plasma very-low density lipoprotein cholesterol concentrations, and liver triglyceride concentrations. To dissect the molecular...
ORGANISM(S): Mus musculus 
2022-10-09 | E-MTAB-12048 | biostudies-arrayexpress
UnknownKRAS-Dependent Glycolytic Reprogramming of Endothelial Cells in Sporadic Arteriovenous Malformations
Not available
S-SCDT-10_1038-S44321-026-00383-Y | biostudies-other
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