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ProteomicsProteomic screen of PACS1 interactors in HCT116 cells
PACS1 syndrome is a neurodevelopmental disorder caused by a recurrent heterozygous missense mutation in PACS1 (p.R203W). We previously showed that PACS1R203W aberrantly potentiates HDAC6 activity, leading to Golgi fragmentation and neuronal deficits through an unresolved mechanism. To elucidate how ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD074970 | Pride
Pacs1 Pacs1 syndrome 
Genomicshuman gut metagenome
Butyrate 2012 Metagenome
PRJNA183959 | ENA
TranscriptomicsThe response of Extra-intestinal Pathogenic Escherichia coli to human serum
In this study the transcriptional response of an ExPEC E. coli strain (CFT073) to human serum was investigated. In response, CFT073 up-regulated expression of iron and manganese acquisition systems and induced expression of iron regulated genes. High osmolarity of serum induced the osmotic shock res...
ORGANISM(S): Escherichia coli 
2013-10-20 | E-MTAB-1985 | biostudies-arrayexpress
UnknownAccelerated methotrexate, vinblastine, doxorubicin, and cisplatin is safe, effective, and efficient neoadjuvant treatment for muscle-invasive bladder cancer: results of a multicenter phase II study with molecular correlates of response and toxicity.
Not available
S-EPMC4050203 | biostudies-literature
UnknownEvaluation of a fast-and-frugal clinical decision algorithm ('pathways') on clinical outcomes in hospitalised patients with COVID-19 treated with anticoagulants.
Not available
S-EPMC9840687 | biostudies-literature
GenomicsMethotrexate Clearance GWAS in Acute Lymphoblastic Leukemia (ALL) Patients

We estimated the plasma clearance of methotrexate from 1279 acute lymphoblastic leukemia (ALL) patients treated on the Children Oncology Group 9904 and 9905 trials (http://clinicaltrials.gov/show/NCT00005585 and

phs000637.v1.p1 | EGA
TranscriptomicsTranscription profiling of human adrenocortical carcinomas (33), adenomas (22), and normal adrenal cortex (10)
Human samples of 33 adrenocortical carcinomas, 22 adrenocortical adenomas, and 10 normal adrenal cortex samples, each from a different patient, had mRNA assays performed using Affymetrix HG_U133_plus_2 arrays, with 54675 probe-sets. Experiment Overall Design: Two supplementary files are attached bel...
ORGANISM(S): Homo sapiens 
2009-02-07 | E-GEOD-10927 | biostudies-arrayexpress
UnknownKi67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).
Not available
S-EPMC5455353 | biostudies-literature
UnknownPhase I First-in-Human Study of Venetoclax in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma.
Not available
S-EPMC5455685 | biostudies-literature
UnknownHigh-dose vincristine sulfate liposome injection for advanced, relapsed, and refractory adult Philadelphia chromosome-negative acute lymphoblastic leukemia.
Not available
S-EPMC4979201 | biostudies-literature
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