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ProteomicsNaa80 acetylates the actin N-terminus impacting the actin cytoskeleton and cell motility
Eukaryotic actins undergo several post-translational modifications during their maturation to enable a fully functional cytoskeletal network. A unique N-terminal processing is conserved in the animal kingdom and includes the removal of the first one or two amino acids as well as N-terminal acetylati...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD006856 | Pride
N-terminal acetylation Nat Actin Human 
ProteomicsAnalysis of N-Glycosylation for SARS-CoV-2 expressed receptor-binding domain VOCs and membrane protein with LC-MS.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect human cells by first attaching to the ACE-2 receptor via its receptor-binding domain (RBD) in the spike protein. We investigated the influence of N-glycosylation sites of the RBD and the membrane (M) protein on IgG antibody bind...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD048930 | panorama
ProteomicsAged Mouse Muscle: Sedentary or Exercised Animals with or without Nicotinamide N-methyltransferase Inhibitor Treatment
Aged (22-mo) female mice (n=35), obtained from the US NIH National Institute on Aging (NIA) Aged Rodent Colony, were randomly assigned to one of four groups: saline-treated sedentary ( n=9), nicotinamide N-methyltransferase inhibitor (NNMTi)-treated sedentary (10 mg/kg body weight; n=9), saline-trea...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-05-07 | MSV000094700 | MassIVE
TranscriptomicsTranscription profiling of human N-Acetyl L-cysteine induced differentiation of NHEK cells in vitro
Gene expression analysis of N-Acetyl L-cysteine induced differentiation of NHEK cells in vitro.
ORGANISM(S): Homo sapiens 
2005-11-30 | E-MEXP-500 | biostudies-arrayexpress
ProteomicsStructural, molecular and cellular impact of the Ogden syndrome mutant N-terminal acetyltransferase hNaa10-Ser37Pro
Abstract still has to be written. The obtained peptide mixtures were introduced into an LC-MS/MS system, the Ultimate 3000 (Dionex, Amsterdam, The Netherlands) in-line connected to an LTQ Orbitrap XL mass spectrometer (Thermo Fisher Scientific, Bremen, Germany). Samples were first loaded on a trapp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-13 | MSV000083564 | MassIVE
ProteomicsMiddle-up analysis of polyclonal IgG-Fc
Middle-up strategy for the analysis of the fragment crystallizable (Fc) region of human plasma immunoglobulins G (IgGs). The use of hydrophilic interaction liquid chromatography (HILIC) and capillary electrophoresis (CE) coupled to mass spectrometry (MS) allowed to get a comprenhesive view of the N-...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-08 | MSV000085388 | MassIVE
ProteomicsN-terminal acetyaltion of Human JunB in yeast expressing all N-terminal acetyltransferases, no NatA enzyme or no NatB enzyne
Define the N-terminal status of overexpressed human JUNB in WT yeast strain, NAA10 Δ strain and NAA20 Δ strain.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-07-03 | PXD047612 | Pride
Junb N-terminal acetyltransferase 
TranscriptomicsExpression profiling by array of Salmonella enterica serovar Typhimurium (SL1344) qseC mutant x wild type
“Stress, survival and virulence: the multi-faceted host/microbial interactions.” Bacteria employ epinephrine and norepinephrine, which converge to distinct bacterial crucial processes, like survival and pathogenicity. A novel stress periplasmic membrane protein belonging to previously described BOF...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2012-05-31 | E-GEOD-38353 | biostudies-arrayexpress
TranscriptomicsExpression data from cochlea isolated from N-myc mutant and wild-type mice at E15
The aim of this study consists in detecting genes regulated by N-myc in the murine cochlea In this data set we present 2688 genes differentially regulated by Nmyc in the murine cochlea. These data serve as a platform for verifying their differential regulation by N-myc via RNA in situ hybridisation ...
ORGANISM(S): Mus musculus 
2014-09-16 | E-GEOD-61406 | biostudies-arrayexpress
ProteomicsN-GlycositeAtlas, a database resource for mass spectrometry-based human N-linked glycoproteins and glycosylation sites
N-Linked glycoprotein is a highly interesting class of proteins for clinical and biological research. The large-scale characterization of N-linked glycoproteins accomplished by mass spectrometry-based glycoproteomics has provided valuable insights into the interdependence of glycoprotein structure a...
ORGANISM(S): Homo sapiens (Human) 
2019-11-08 | PXD005143 | Pride
Mass spectrometry Glycoprotein Protein glycosylation Database Glycoproteome 
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