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TranscriptomicsHIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs
Over the last decade, small noncoding RNA molecules such as microRNAs (miRNAs) have emerged as critical regulators in the expression and function of eukaryotic genomes. It has been suggested that viral infections and neurological disease outcome may also be shaped by the influence of small RNAs. Thi...
ORGANISM(S): Homo sapiens 
2012-12-07 | E-GEOD-42423 | biostudies-arrayexpress
TranscriptomicsTranscriptome transfer provides a model for understanding the phenotype of cardiomyocytes
We show that the transfer of the adult ventricular myocyte (AVM) transcriptome into either a fibroblast or an astrocyte converts the host cell into a cardiomyocyte. Transcriptome-effected cardiomyocytes (tCardiomyocytes) display morphologies, immunocytochemical properties, and expression profiles of...
ORGANISM(S): Mus musculus 
2011-06-23 | E-GEOD-30164 | biostudies-arrayexpress
TranscriptomicsAndersson_et_al_2013
LGL leukemia is chronic clonal lymphoproliferative disorder, characterized by expansion of cytotoxic CD8+ T-cells or NK-cells. We compared gene expression of 2 LGL leukemia patients with STAT3 mutation (Patients 11 and 12) and 2 LGL leukemia patients without STAT3/STAT5b mutation (Patients 9 and 10)...
ORGANISM(S): Homo sapiens 
2013-11-14 | E-MTAB-2068 | biostudies-arrayexpress
TranscriptomicsHIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs.
Over the last decade, small noncoding RNA molecules such as microRNAs (miRNAs) have emerged as critical regulators in the expression and function of eukaryotic genomes. It has been suggested that viral infections and neurological disease outcome may also be shaped by the influence of small RNAs. Thi...
ORGANISM(S): Homo sapiens 
2013-02-12 | E-GEOD-44265 | biostudies-arrayexpress
TranscriptomicsDeregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders
Studies have shown that HIV-infected patients develop neurocognitive disorders characterized by neuronal dysfunction. The lack of productive infection of neurons by HIV suggests that viral and cellular proteins, with neurotoxic activities, released from HIV-1-infected target cells can cause this neu...
ORGANISM(S): Homo sapiens 
2012-12-07 | E-GEOD-42424 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli K-12 yliH and yceP biofilm expression relative to wild type
Expression in biofilm cells of mutants yceP and yliH relative to biofilm cells of E. coli K-12 wild type strain Experiment Overall Design: All strain cultured in LB glu, biofilm isolated from glass wool after culturing for 24 hrs.
ORGANISM(S): Escherichia coli 
2008-06-12 | E-GEOD-3937 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis inflorescence stalks of intact plants after infection with A. tumefaciens
The intention of these gene expression analysis was to study host responses to an infection with Agrobacterium tumefaciens at different stages of crown gall development. Therefore the transcriptome of infected inflorescence stalk tissue and mature crown galls of Arabidopsis thaliana (WS-2) was deter...
ORGANISM(S): Arabidopsis thaliana 
2009-12-02 | E-GEOD-14106 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis to identify Tween 20 inducible genes
Polyethylene glycol sorbitan monoacylates (Tween) are detergents of widespread use in plant sciences. We show them, notably Tween 20, to cause a rapid and complex change in transcript abundance which bears all characteristics of a PAMP / elicitor-induced defense response, and they do so at concentra...
ORGANISM(S): Arabidopsis thaliana 
2009-11-10 | E-GEOD-5513 | biostudies-arrayexpress
GenomicsDNA-seq of differentially induced promoter regions in E. coli UTI89 strain grown in either J82 bladder epithelial cells, urine, DMEM or LB medium.
The method DFI-seq was developed to enable identification of differentially expressed genes in uropathogenic E. coli strain UTI89 during growth in human urine and in bladder epithelial cells. By utilising this new method, the aim was to identify novel virulence genes in UTI89. DFI-seq is a combinati...
ORGANISM(S): Escherichia coli UTI89 
2017-05-01 | E-MTAB-5657 | biostudies-arrayexpress
TranscriptomicsDeregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders.
Studies have shown that HIV-infected patients develop neurocognitive disorders characterized by neuronal dysfunction. The lack of productive infection of neurons by HIV suggests that viral and cellular proteins, with neurotoxic activities, released from HIV-1-infected target cells can cause this neu...
ORGANISM(S): Homo sapiens 
2013-02-12 | E-GEOD-44266 | biostudies-arrayexpress
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