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MetabolomicsMetabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

BACKGROUND: One-third of inflammatory bowel disease (IBD) patients show no response to infliximab (IFX) induction therapy, and approximately half of patients responding become unresponsive over time. Thus, identification of potential treatment response biomarkers are of great cl...

2022-01-13 | MTBLS239 | MetaboLights
ProteomicsComparative proteomics of salt stressed own rooted and 110R grafted Thompson Seedless grapevines
Salt stress is a rising threat to agriculture system. The accumulation of salts near the plant roots hampers the normal uptake of water causing osmotic stress and ionic toxicity to the plant. Thompson Seedless is a popular table grape variety of Vitis vinifera L., which is sensitive to salt stress w...
ORGANISM(S): Vitis vinifera (Grape) 
2020-01-27 | PXD015515 | Pride
Lc-msms Thompson seedless Vitis : label-free Synapt-g1 Hdms Salt stress Shotgun Grapevine Leaf Progenesis-qip 
UnknownVvHDZ28 positively regulate salicylic acid biosynthesis during seed abortion in Thompson Seedless.
Not available
S-EPMC8428834 | biostudies-literature
UnknownTelomere-to-telomere and gap-free genome assembly of a susceptible grapevine species (Thompson Seedless) to facilitate grape functional genomics.
Not available
S-EPMC10822838 | biostudies-literature
GenomicsSalmonella enterica subsp. enterica serovar Thompson str. RM6836
Salmonella enterica subsp. enterica serovar Thompson str. RM6836 Genome sequencing
PRJNA70669 | ENA
ProteomicsGrapevine Leaf proteome - Overexpression of a stress-responsive U-box protein gene VaPUB affects the accumulation of resistance related proteins in Vitis vinifera 'Thompson Seedless'
To investigate differentially accumulated proteins caused by transgenic events, comparative proteomic analysis using two-dimensional polyacrylamide gel electrophoresis was employed for Vitis vinifera ‘Thompson seedless’ leaves and transgenic Vitis vinifera ‘Thompson seedless’ leaves. Obtained protei...
ORGANISM(S): Vitis vinifera (Grape) 
2017-01-04 | PXD005570 | Pride
Vitis Maldi-tof/tof 
TranscriptomicsEvaluation of covS polymorphisms on group A streptococcal global gene expression
We sought to determine how single amino acid changes in the active site of CovS autophosphorylation and subsequent phosphorylation of the response regulator CovR affect the gene expression profile of group A streptococcus There were 6 strains analyzed, each in quadruplicate replicates: 1) wild-type ...
ORGANISM(S): Streptococcus sp. 'group A' 
2015-01-24 | E-GEOD-65226 | biostudies-arrayexpress
MetabolomicsIntegrating two chromatographies in a co-fractionation mass spectrometry approach improved protein-metabolite interactions (PMIs) mapping capabilities and revealed novel protein-ligand pairings in Escherichia coli.
The protein-metabolite interactome remains understudied. We previously developed a co-fractionation mass-spectrometry-based approach called PROMIS to address this gap. PROMIS relies on size separation chromatography of protein-metabolite complexes from lysates, followed by proteomics and metabolomic...
2025-04-25 | MTBLS9098 | MetaboLights
GenomicsVitis vinifera cultivar:Thompson seedless
Vitis vinifera cultivar:Thompson seedless Transcriptome or Gene expression
PRJNA525320 | ENA
MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
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