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To investigate the specific gene expression program by which mutant-p53 and Pin1 control invasion and metastasis in breast cancer cells, we compared the transcriptomic profile of control, mutant-p53 depleted or Pin1 depleted MDA-MB-231 cells. MDA-MB-231 cells were transfected twice with siRNA agains...
ORGANISM(S): Homo sapiens 
A comprehensive characterisation and analysis of human breast cancers through whole-genome sequencing.
A comprehensive characterisation and analysis of 560 human breast cancers through genome-wide approaches including genomics, transcriptomics and epigenomics.
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
Mitochondrial genomes are separated from the nuclear genome for most of the cell cycle by the nuclear double membrane, intervening cytoplasm and the mitochondrial double membrane. Despite these physical barriers we show that somatically acquired mitochondrial-nuclear genome fusion sequences are pres...
Affymetrix SNP6.0 breast cancer genome sequencing data
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