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RNA sequencing of wild-type or Interferon Alpha receptor 1 Knockout MEF cells treated with DMSO or the Broad-spectrum Caspase Inhibitor Q-VD-OPh The mechanism by which cells undergo death determines whether dying cells trigger inflammatory responses or remain immunologically silent. Mitochondria pla...
ORGANISM(S): Mus musculus 
To investigate the specific gene expression program by which mutant-p53 and Pin1 control invasion and metastasis in breast cancer cells, we compared the transcriptomic profile of control, mutant-p53 depleted or Pin1 depleted MDA-MB-231 cells. MDA-MB-231 cells were transfected twice with siRNA agains...
ORGANISM(S): Homo sapiens 
A common reference experiment design was performed. mRNAs from 149 New Zealand colorectal cancer samples were labeled with Cy5 and a common reference RNA from 12 cell lines were labeled with Cy3. Data were log2 transformed and normalized. Class prediction was performed to identify genes capable of p...
ORGANISM(S): Homo sapiens 
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