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Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, with chronic hepatitis B virus (HBV) infection being a major contributor to its development. Despite this, effective treatment for HBV-associated HCC remains a significant challenge. In this study, we combined the s...
2025-07-17 | MTBLS12196 | MetaboLights
A comparison of gene expression in the mammary gland of lactating mice at day 9 after parturition between Akt -/- and wildtype individuals.
ORGANISM(S): Mus musculus 
An experiment to compare the gene expression between two stages of murine mammary gland development; day 18 of pregnancy and lactating mammary gland 9 days post parturition.
ORGANISM(S): Mus musculus 
Clinical Implications of Genomic Alterations in the Tumour and Circulation of Pancreatic Cancer Patients
Pancreatic adenocarcinoma has the worst mortality of any solid cancer. To evaluate the clinical implications of genomic alterations in this tumor type, we performed whole-exome analyses of 24 tumors, targeted genomic analyses of 77 tumors, and used non-invasive approaches to examine tumor-specific ...
Data Access Committee EGAC00001000358
More than 50% of patients with chondrosarcomas exhibit gain-of-function mutations in either isocitrate dehydrogenase 1 (IDH1) or IDH2. In this study, we performed genome-wide CpG methylation sequencing of chondrosarcoma biopsies and found that IDH mutations were associated with DNA hypermethylation ...
ORGANISM(S): Homo sapiens 
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