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MetabolomicsIntegrating two chromatographies in a co-fractionation mass spectrometry approach improved protein-metabolite interactions (PMIs) mapping capabilities and revealed novel protein-ligand pairings in Escherichia coli.
The protein-metabolite interactome remains understudied. We previously developed a co-fractionation mass-spectrometry-based approach called PROMIS to address this gap. PROMIS relies on size separation chromatography of protein-metabolite complexes from lysates, followed by proteomics and metabolomic...
2025-04-25 | MTBLS9098 | MetaboLights
TranscriptomicsComparative genome hybridization for Lactobacillus casei
Lactobacillus casei is remarkably adaptive to diverse habitats. To understand the evolution and adaptation of Lb. casei strains isolated from different environments, the gene content of 22 Lb. casei strains isolated from various habitats (cheeses, n=8; plant materials, n=8; and human sources, n=6) w...
ORGANISM(S): Lactobacillus casei 
2010-06-21 | E-GEOD-15030 | biostudies-arrayexpress
UnknownNew ZW4864 Derivatives as Small-Molecule Inhibitors for the β-Catenin/BCL9 Protein-Protein Interaction.
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S-EPMC9109161 | biostudies-literature
UnknownJPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium.
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S-EPMC4291346 | biostudies-literature
UnknownEffect of stretching on inflammation in a subcutaneous carrageenan mouse model analyzed at single-cell resolution.
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S-EPMC10773986 | biostudies-literature
UnknownExternal validation of an opioid misuse machine learning classifier in hospitalized adult patients.
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S-EPMC7967783 | biostudies-literature
UnknownPredictors of operative difficulty in robotic low anterior resection for rectal cancer.
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S-EPMC9701150 | biostudies-literature
UnknownHypofractionated stereotactic re-irradiation with pembrolizumab and bevacizumab in patients with recurrent high-grade gliomas: results from a phase I study.
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S-EPMC8041351 | biostudies-literature
UnknownDevelopment and multimodal validation of a substance misuse algorithm for referral to treatment using artificial intelligence (SMART-AI): a retrospective deep learning study.
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S-EPMC9159760 | biostudies-literature
UnknownMyeloid PTP1B deficiency protects against atherosclerosis by improving cholesterol homeostasis through an AMPK-dependent mechanism.
Not available
S-EPMC10568790 | biostudies-literature
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