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MetabolomicsDiagnostic metabolite biomarkers of chronic typhoid carriage
Background: Salmonella Typhi and Salmonella Paratyphi A are the agents of enteric (typhoid) fever; both can establish chronic carriage in the gallbladder. Chronic Salmonella carriers are typically asymptomatic, intermittently shedding bacteria in the feces, and contributing to disease transmission. ...
2018-01-17 | MTBLS579 | MetaboLights
UnknownMulticenter, Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Pravastatin Added to First-Line Standard Chemotherapy in Small-Cell Lung Cancer (LUNGSTAR).
Not available
S-EPMC5455702 | biostudies-literature
UnknownSWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer.
Not available
S-EPMC4417730 | biostudies-literature
TranscriptomicsGenome-wide transcriptional responses to benzo[a]pyrene and clofibrate in the tunicate Oikopleura dioica
Animals have developed extensive mechanisms of response to xenobiotic chemical attacks. Although recent genome surveys have suggested a broad conservation of the chemical defensome across metazoans, global gene expression responses to xenobiotics are not known in most invertebrates. Here, using high...
ORGANISM(S): Oikopleura dioica 
2013-02-05 | E-GEOD-33818 | biostudies-arrayexpress
ProteomicsSerum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | MassIVE
UnknownEmergency department presentations in the Southern District of New Zealand during the 2020 COVID-19 pandemic lockdown.
Not available
S-EPMC8013615 | biostudies-literature
TranscriptomicsSpinal Ependymoma Gene Expression Data
Purpose: Myxopapillary ependymoma (MPE) is a distinct histological variant of ependymoma arising commonly in the spinal cord. Despite an overall favorable prognosis, distant metastases, subarachnoid dissemination, and late recurrences have been reported. Currently the only effective treatment for M...
ORGANISM(S): Homo sapiens 
2015-09-02 | E-GEOD-66787 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wheat B1118-8 4(6) line with its background control-Cadenza bread wheat line. Transcriptomes analysis was performed in endosperm tissue (14 and 28 days post anthesis-dpa) and in leaf tissue (8 days post germination dpg)
B1118-8-4 expresses five HMW subunits encoded by Glu-B1 (14, 15) and Glu D1 (5, 10) and transgene Glu-A1 (Ax1).Cadenza does not express Glu-A1 (Ax1. B111-8-8-4 (6)transgenic wheat line was produced by co-transformation with two plasmids: one of the plasmids carring the transgene HMW-GS 1Ax1 (Halford...
ORGANISM(S): Triticum aestivum 
2005-10-05 | E-MEXP-311 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wheat GF- TRANS_B102,1-1 vs Conv.bred_L88-18 transgenic lines endosperm tissue (14 and 28 days post anthesis-dpa) and in leaf tissue (8 days post germination ?dpg)
The high molecular weight (HMW) subunits of wheat glutenin are synthesised only in the starchy endosperm tissue of the developing wheat grain. We compared the expressed genomes of the transgenic wheat line B102,1-1 (Rooke et al. Transgene inheritance, segregation and expression in bread wheat. Euphy...
ORGANISM(S): Triticum aestivum 
2005-10-05 | E-MEXP-309 | biostudies-arrayexpress
TranscriptomicsAffect of antiviral ribavirin on YFV WT and vaccine strains.
Live-attenuated viral vaccines have been successfully used to combat infectious disease for decades but due to their empirical derivation, little is known about their mechanisms of attenuation. This lack of understanding makes the development of next generation live attenuated vaccines difficult. Th...
ORGANISM(S): Yellow fever virus 
2020-01-01 | E-MTAB-8504 | biostudies-arrayexpress
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