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TranscriptomicsA Snapshot of Copy Number Variation in the pig genome
Recents studies in mammalian genomes have uncovered the extent of copy number variation (CNV) that contributes to phenotypic diversity, including health and disease status. Here we report the first glimpse of CNVs in the pig genome covering part of the chromosomes 4, 7, 14 and 17 already sequenced a...
ORGANISM(S): Sus scrofa 
2010-06-21 | E-GEOD-10753 | biostudies-arrayexpress
ProteomicsMechanistic Divergence Between SOS Response Activation and Antibiotic-Induced Plasmid Conjugation in E. coli
Project description: Plasmids, frequently carried by environmental and pathogenic bacteria, play a critical role in rapid dissemination of antibiotic resistance through conjugation. The use of antibiot-ics further induces this conjugative transmission between bacteria and thereby plays a role in the...
ORGANISM(S): Escherichia coli 
2025-05-08 | PXD063721 | Pride
Sos response  conjugation  antibiotics  e. coli  inci1 
UnknownThe multi-channel potentiostat: Development and evaluation of a scalable mini-potentiostat array for investigating electrochemical reaction mechanisms.
Not available
S-EPMC8445456 | biostudies-literature
ProteomicsProteomic profiling of TGFBIp-null mouse corneas reveals minor changes in the extracellular matrix composition supportive of TGFBI knockdown as therapy against TGFBI-linked corneal dystrophies
TGFBIp is a constituent of the extracellular matrix in many human tissues including the cornea, where it is one of the most abundant proteins expressed. TGFBIp interacts with type I, II, IV, VI and XII collagens as well as several members of the integrin family, suggesting that it plays an important...
ORGANISM(S): Mus musculus (Mouse) 
2017-11-14 | PXD006494 | Pride
Ecm Tgfbip Cornea Periostin Itraq Lc-ms/ms 
ProteomicsTowards unravelling biological mechanisms behind radiation-induced oral mucositis via mass spectrometry-based proteomics
Objective: Head and neck cancer (HNC) accounts for almost 850,000 new cases per year. Radiotherapy (RT) is used to treat the majority of these patients. A common side-effect of RT-treatment is onset of oral mucositis: a painful irritation and swelling in mouth, which decreases the quality of life an...
ORGANISM(S): Homo sapiens (Human) 
2023-06-09 | PXD040398 | Pride
Keratinocytes Interferon response Stat phosphorylation Radiotherapy Mass spectrometry-based proteomics Biomarker Mcm complex 
TranscriptomicsSalmonella under environmental stress
The aim of this study is to investigate the transcriptional response of S. Typhimurium to heat, osmotic, oxidative and acid stress under anoxic and oxic conditions and to non-stressed anoxic conditions.
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2013-11-11 | E-MTAB-1804 | biostudies-arrayexpress
ProteomicsProteome profiles of primary pancreatic ductal adenocarcinomas undergoing adjuvant chemoradiation link ALDH1A1 to early local recurrence and chemoradiation resistance
Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis with very frequent post-surgical local recurrence. The combination of adjuvant chemotherapy with radiotherapy is under consideration to achieve a prolonged disease-free survival (DFS). To date, few studies have determined protein profiles ...
ORGANISM(S): Homo sapiens (Human) 
2018-09-11 | PXD009254 | Pride
Maoa Chemoradiation Aldh1a1 
TranscriptomicsDistribution of segmental duplications in the context of higher order chromatin organisation of human chromosome 7
Background Segmental duplications (SDs) are not evenly distributed along chromosomes. The reasons for this biased susceptibility to SD insertion are poorly understood. Accumulation of SDs is associated with increased genomic instability, which can lead to structural variants and genomic disorders su...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-41356 | biostudies-arrayexpress
GenomicsAn Estrogen Receptor α-bound Human Chromatin Interactome
We developed Chromatin Interaction Analysis by Paired-End Tag sequencing (ChIA-PET) for de novo detection of global chromatin interactions, and comprehensively mapped the chromatin interaction network bound by estrogen receptor α (ERα) in the human genome. We performed 454 and Illumina sequencing an...
ORGANISM(S): Homo sapiens 
2009-09-11 | E-GEOD-18046 | biostudies-arrayexpress
TranscriptomicsCUT&RUN of erythroblasts upon perturbation of gamma-hemoglobin repressors (part II)
Through high throughput compound screening, we've identified compounds that induce the expression of fetal hemoglobin. This study contains CUT&RUN data of a novel target, WIZ.
ORGANISM(S): Homo sapiens 
2024-06-19 | E-MTAB-13890 | biostudies-arrayexpress
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