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TranscriptomicsThrombospondin-1 type 1 repeats in a model of inflammatory bowel disease: genetic profile and therapeutic effects
Thrombospondin 1 (TSP-1) is an anti-angiogenic matricellular protein with regulatory functions in inflammation and cancer. The type 1 repeats (TSR) domains of TSP-1 have been shown to interact with a wide range of proteins that result in the anti-angiogenic and anti-tumor properties of TSP-1. To eva...
ORGANISM(S): Mus musculus 
2014-08-26 | E-GEOD-32697 | biostudies-arrayexpress
ProteomicsO-fucosylation of Thrombospondin Type I Repeats on Thrombospondin 1 is dispensable for trafficking to Platelets
Thrombospondin 1 (THBS1) is a secreted extracellular matrix glycoprotein that regulates a variety of cellular and physiological processes. THBS1’s diverse functions are attributed to interactions between the modular domains of THBS1 with an array of proteins found in the extracellular matrix. THBS1’...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-02 | PXD037158 | Pride
Pofut2/o-fucosylation/c-mannosylation/thrombospondin 1/protein trafficking 
ProteomicsO-Fucosylation of ADAMTSL2 Thrombospondin Type 1 Repeats is Required for Secretion and is Impacted by Geleophysic Dysplasia-Causing Mutations
A disintegrin-like and metalloprotease domain with thrombospondin type 1 repeats-like 2 (ADAMTSL2) is a matricellular protein that interacts with latent TGF-b binding protein 1 and fibrillin-1. ADAMTSL2 mutations cause an autosomal recessive connective tissue disorder named geleophysic dysplasia 1 (...
ORGANISM(S): Mus musculus (Mouse) 
2020-10-01 | PXD018902 | Pride
Geleophysic dysplasia Thrombospondin type 1 repeats Tsr glycosylation Adamtsl2 o-fucosylation 
TranscriptomicsThrombospondin-1 type 1 repeats in a model of inflammatory bowel disease: genetic profile and therapeutic effects
Thrombospondin 1 (TSP-1) is an anti-angiogenic matricellular protein with regulatory functions in inflammation and cancer. The type 1 repeats (TSR) domains of TSP-1 have been shown to interact with a wide range of proteins that result in the anti-angiogenic and anti-tumor properties of TSP-1. To eva...
ORGANISM(S): Mus musculus 
2014-08-26 | GSE32697 | GEO
UnknownO-fucosylation of thrombospondin type I repeats is dispensable for trafficking thrombospondin 1 to platelet secretory granules.
Not available
S-EPMC10191222 | biostudies-literature
UnknownThrombospondin-1 type 1 repeats in a model of inflammatory bowel disease: transcript profile and therapeutic effects.
Not available
S-EPMC3318003 | biostudies-literature
UnknownAlternative chemistries for the synthesis of thrombospondin-1 type 1 repeats.
Not available
S-EPMC2906232 | biostudies-literature
UnknownDistinct C-mannosylation of netrin receptor thrombospondin type 1 repeats by mammalian DPY19L1 and DPY19L3.
Not available
S-EPMC5347603 | biostudies-literature
UnknownEssential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.
Not available
S-EPMC3174348 | biostudies-literature
UnknownPost-translational modification of thrombospondin type-1 repeats in ADAMTS-like 1/punctin-1 by C-mannosylation of tryptophan.
Not available
S-EPMC2781554 | biostudies-literature
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