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ProteomicsBlocking CXCR4+ CD4+ T cells reprograms Treg-mediated immunosuppression via modulating the Rho-GTPase/NF-κB pathway
Clinical trials have demonstrated that CXCR4 antagonists enhance the efficacy of immunotherapy in cancers by reducing regulatory T (Treg) cells, elucidating how certain mechanisms of CXCR4 in affecting Treg cells are essential for developing immunotherapeutic strategies.
ORGANISM(S): Homo Sapiens 
2024-11-25 | PXD058262 |
ProteomicsStreptococcus suis, LC-MSMS, EGCG
EGCG effect proteomic profiles of Streptococcus suis
ORGANISM(S): Streptococcus suis 05ZYH33 
2022-10-14 | PXD026047 | Pride
Streptococcus suis Lc-msms，egcg 
Proteomicsstreptococcus suis LC-MS/MS - MnmE, a Central tRNA-Modifying GTPase, Is Essential for the Growth, Pathogenicity, and Arginine Metabolism of Streptococcus suis Serotype 2
Streptococcus suis is an important pathogen in pigs and can also cause severe infections in humans. However, little is known about proteins associated with cell growth and virulence of S. suis. In this study, a GTPase MnmE homologue was identified in a Chinese isolate (SC19) that drives a tRNA modif...
ORGANISM(S): Streptococcus suis SC149 
2019-11-13 | PXD012716 | Pride
Ss2 Tmt Mnme 
UnknownTailoring coordination environments of single-atom electrocatalysts for hydrogen evolution by topological heteroatom transfer.
Not available
S-EPMC10981667 | biostudies-literature
UnknownLong non-coding RNA LINC01133 mediates nasopharyngeal carcinoma tumorigenesis by binding to YBX1.
Not available
S-EPMC6511644 | biostudies-literature
UnknownCharacteristics of bacterial community in eyelashes of patients with Demodex blepharitis.
Not available
S-EPMC10868039 | biostudies-literature
UnknownPulmonary Delivery of Nanoparticle-Bound Toll-like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer.
Not available
S-EPMC7531260 | biostudies-literature
ProteomicsStable isotope-resolved metabolomics reveals the abnormal brain glucose catabolism in depression based on chronic unpredictable mild stress rats
The severe harm of depression to human life has attracted great attention to neurologists, but its pathogenesis is extremely complicated and has not yet been fully elaborated. Here, we provided a new strategy for revealing the specific pathways of abnormal brain glucose catabolism in depression, whi...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-06-10 | PXD025548 | Pride
Stable isotope-resolved metabolomics Brain glucose catabolism Depression Liquid chromatography-mass spectrometry Mitochondrial structure and function 
UnknownThe risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression.
Not available
S-EPMC9187238 | biostudies-literature
ProteomicsDesign and Development of DNA Damage Chemical Inducers of Proximity (DD-CIP) for Targeted Cancer Therapy
Many chemotherapies are effective against cancers that display high levels of genome instability by disrupting or overwhelming the DNA damage response to induce cell death. PARP inhibitors (PARPi) exploit this vulnerability by stalling DNA repair particularly in homologous recombination (HR)-deficie...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-12-06 | MSV000100135 | MassIVE
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