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MetabolomicsCell Atlas and Novel Signal Processing Strategy in Primate Insular Cortex

The anterior insular cortex (AIC) is a critical hub integrating exteroceptive and interoceptive information into high-order cognition, yet its neural basis remains incompletely understood. Here, by combining whole-cell-based single-cell transcriptomics with Patch-seq recordings, we resolved and c...

2026-02-28 | MTBLS13927 | MetaboLights
MetabolomicsA metabolome atlas of mouse brain on the global metabolic signature dynamics following short-term fasting
Calorie restriction (CR) or a fasting regimen is considered one of the most potent non-pharmacological interventions to prevent chronic metabolic disorders, ameliorate autoimmune diseases, and attenuate aging. Despite efforts, the mechanisms by which CR improves health, particularly brain health, ar...
2025-07-31 | MTBLS8006 | MetaboLights
MetabolomicsAn Atlas of Ferroptosis-induced Secretomes promotes Macrophage priming
Cells undergoing regulated necrosis systemically communicate with the immune system via release of protein and non-protein secretomes. Ferroptosis is a recently described iron-dependent type of regulated necrosis driven by massive lipid peroxidation. While membrane rupture occurs during ferroptosis,...
2025-03-04 | MTBLS9798 | MetaboLights
MetabolomicsA Metabolome Atlas of Grape Biodiversity
Grapevine (Vitis spp.) is one of the world’s most economically, culturally, and biologically important fruit crops, with remarkable diversity spanning thousands of V. vinifera cultivars together with rootstocks and wild relatives. Yet grapevine biodiversity has never been systematically explored at ...
2026-08-25 | MTBLS14377 | MetaboLights
TranscriptomicsAn Atlas of Bovine Gene Expression Reveals Novel Distinctive Tissue Characteristics and Evidence for Improving Genome Annotation
Background: A comprehensive transcriptome survey, or "gene atlas", provides information essential for a complete understanding of the genomic biology of an organism. We present an atlas of RNA abundance for 92 adult, juvenile and fetal cattle tissues and 3 cattle cell lines. Results: The ...
ORGANISM(S): Bos taurus 
2010-09-28 | E-GEOD-21544 | biostudies-arrayexpress
MetabolomicsTen Mouse Organs Proteome and Metabolome Atlas from Adult to Aging

The complexity of the aging process, encompassing numerous organs and systems, poses a significant challenge in identifying and targeting key factors that drive age-related decline. The multi-organ synchronous molecular intricacies underlying natural aging remain elusive. Here we presented a data...

2025-08-29 | MTBLS10642 | MetaboLights
MetabolomicsAn Atlas of Inter-Organ Metabolite Trafficking in Health and Atherogenic Conditions

Mammalian organs continuously exchange circulating metabolites for organismal health and survival. However, the landscape of this fundamental process and its perturbation by diet and disease is unknown. Using arteriovenous metabolomics, tissue transcriptomics, hormone arrays and multiple metaboli...

2025-05-12 | MTBLS10288 | MetaboLights
MetabolomicsAtlas of one-carbon metabolism in conventional and germ-free mice reveals folate as a key determinant of biochemical pathways

Folates participate in the one-carbon metabolism (OCM) cycle, supporting many biochemical pathways. Existing methods to profile folate are limited in the diversity of vitamers they measure and the samples they profile. We present a metabolomics workflow for stable extraction, separation, and meas...

2026-02-10 | MTBLS13484 | MetaboLights
TranscriptomicsA Gene Expression Atlas of the Domestic Pig
A Gene Expression Atlas of the Domestic Pig
ORGANISM(S): Sus scrofa 
2012-09-01 | E-MTAB-1183 | biostudies-arrayexpress
TranscriptomicsSingle-cell identification of L1HS-Ta retrotransposons in preimplantation embryos by ATLAS-seq
We used ATLAS-seq to comprehensively map the genomic location of LINE-1 elements belonging to the youngest and potentially polymorphic subfamily (L1HS-Ta). This was performed in single-cells of 2 preimplantation embryos (E3 and E6) as well as from the remaining inner cell mass (denoted T). In brief,...
ORGANISM(S): Homo sapiens 
2023-09-30 | E-MTAB-8616 | biostudies-arrayexpress
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