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ProteomicsEstablishment of titration-based control of DNA replication in Escherichia coli
Escherichia coli couples the initiation of DNA replication with cell size by modulating the activity of the replication initiator protein DnaA. The activity of DnaA is regulated both by its interconversion between an active and inactive form and by its titration on chromosomal binding sites. Whereas...
ORGANISM(S): Escherichia coli 
2026-09-10 | PXD075568 | Pride
Hyper-replicative stress Dnaa-atp/dnaa-adp switch Replication forks Dnaa boxes Dnaa Titration-based control of dna replication 
ProteomicsThe Escherichia coli replication initiator DnaA is titrated on the chromosome
DNA replication initiation is orchestrated in bacteria by the replication initiator DnaA. Two models for regulation of DnaA activity in Escherichia coli have been proposed: the switch between an active and inactive form and the titration of DnaA on the chromosome. Although proposed decades ago, expe...
ORGANISM(S): Escherichia coli 
2025-07-28 | PXD064841 | Pride
Titration model Single-particle tracking photoactivatable localisation microscopy Switch model Dnaa protein Oric Dnaa boxes chromosome binding Data Replication initiator 
UnknownThe Escherichia coli replication initiator DnaA is titrated on the chromosome.
Not available
S-EPMC12371093 | biostudies-literature
UnknownInhibition of porcine reproductive and respiratory syndrome virus replication in vitro using DNA-based short antisense oligonucleotides.
Not available
S-EPMC4534064 | biostudies-literature
UnknownTranscriptional inactivation of a regulatory site for replication of Vibrio cholerae chromosome II.
Not available
S-EPMC1567695 | biostudies-literature
GenomicsHEK293 cells (HEK293-CT) and HEK293 cells stably over-expressing the BAHD1 gene (HEK-BAHD1)
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-12-11 | E-GEOD-51868 | biostudies-arrayexpress
UnknownNovel histone H3 binding protein ORF158L from the Singapore grouper iridovirus.
Not available
S-EPMC3165850 | biostudies-literature
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