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ProteomicsProteomic analysis of E. coli MG1655 after removal of oriC
The project aim was to describe proteomic changes in E. coli MG1655 strain after removal of oriC. Temperature-sensitive transcriptional repressor cI857 and its target promoter was used to control the expression of a serine recombinase from bacteriophage phiC31 (phiC31 integrase). cI857 is a temperat...
ORGANISM(S): Escherichia coli 
2021-12-15 | PXD029931 | Pride
Growth decoupling Switcher Oric E. coli 
UnknownORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Nab-Paclitaxel in Patients with Advanced Solid Tumors.
Not available
S-EPMC11396014 | biostudies-literature
GenomicsThe stringent response inhibits DNA replication initiation in E. coli by modulating supercoiling of oriC
The stringent response inhibits DNA replication initiation in E. coli by modulating supercoiling of oriC
PRJNA528271 | ENA
TranscriptomicsGenome-wide binding of replication initiation proteins in Bacillus subtilis
Initiation of DNA replication requires binding of the initiator protein, DnaA, to specific binding sites in the chromosomal origin of replication, oriC. In low G+C Gram-positive bacteria, the primosomal proteins DnaD and DnaB, in conjunction with loader ATPase DnaI, load the replicative helicase at ...
ORGANISM(S): Bacillus subtilis 
2010-12-07 | E-GEOD-23686 | biostudies-arrayexpress
UnknownPhase I Study of ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer Progressing on Enzalutamide.
Not available
S-EPMC10947849 | biostudies-literature
UnknownMycobacterium tuberculosis oriC sequestration by MtrA response regulator.
Not available
S-EPMC4700885 | biostudies-literature
TranscriptomicsThe stringent response inhibits DNA replication initiation in E. coli by modulating supercoiling of oriC
The stringent response enables bacteria to respond to a variety of environmental stresses, especially various forms of nutrient limitation. During the stringent response the cell produces large quantities of the nucleotide alarmone ppGpp, which modulates many aspects of cell physiology, including re...
ORGANISM(S): Escherichia coli K-12 
2019-06-11 | GSE128606 | GEO
UnknownDevelopment of oriC-plasmids for use in Mycoplasma hyorhinis.
Not available
S-EPMC5587638 | biostudies-literature
TranscriptomicsRegulation of initiation of chromosome replication by oriC-proximal DnaA-box clusters in Bacillus subtilis
Comparison of transcriptions in wild_type, delta-6 (deletion of six DnaA-box clusters (DBCs)), delta-5 and delta-DBC[yydA-yycS] strains, to see effect of the DBCs on transcription of neighboring genes and DnaA-regulated genes.
ORGANISM(S): Bacillus subtilis 
2011-07-01 | E-MEXP-3069 | biostudies-arrayexpress
UnknownHost specificity of mollicutes oriC plasmids: functional analysis of replication origin.
Not available
S-EPMC275544 | biostudies-literature
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