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MetabolomicsArtificial fermentation with trichome exudate improves microbial community composition and leaf quality in cigar tobacco
Diterpenoids and sucrose esters are synthesized in cigar tobacco leave (CTLs) trichomes and secreted onto leaf surface as trichome exudate (TE), contributing to sensory quality.To reveal the mechanism by which TE affects CTLs quality, this study employed the half-leaf method, utilizing tobacco extra...
2026-06-17 | MTBLS14776 | MetaboLights
MetabolomicsAnalysis of the Effects of Bacillus velezensis HJ-16 Inoculation on Tobacco Leaves Based on Multi-omics Methods

In this study, a strain isolated from the surface of flue-cured tobacco leaves, identified as Bacillus velezensis HJ-16, was applied in the solid-state fermentation of tobacco leaves. This strain, known for producing thermally stable enzymes, including amylase, cellulase, and protease, s...

2024-10-23 | MTBLS11080 | MetaboLights
MetabolomicsEnhancing sensory quality of heat-not-burn tobacco via bioaugmentation with Cytobacillus oceanisediminis C4 and Amylase

Tobacco fermentation is a crucial process for improving tobacco quality by reducing undesirable substances. In this study, an enzyme–microbe combined fermentation strategy was established and evaluated. Cytobacillus oceanisediminis C4 combined with amylase pretreatment was applied in the fermenta...

2025-12-26 | MTBLS13570 | MetaboLights
MetabolomicsSoil legacy effects in Soybean Intercropping Enhance Tobacco Resistance to Fusarium Root Rot

Soil-borne diseases, with their high incidence and frequency in monoculture systems, pose a major challenge in contemporary agricultural production. Intercropping can promote beneficial soil legacy effects, thereby effectively mitigating the occurrence and damage of soil-borne diseases. In this s...

2025-09-05 | MTBLS12940 | MetaboLights
MetabolomicsNon-targeted metabolomics data from solid fermented tobacco leaves derived from Enterobacter hormaechei

Enterobacter hormaechei-mediated solid-state fermentation (SSF) metabolomics in tobacco leaves remains underexplored. Using gas chromatography coupled with high-resolution mass spectrometry (GC-HRMS), we generated a time-resolved metabolomic dataset revealing 88 dynamically regulated metabolites,...

2025-11-12 | MTBLS12343 | MetaboLights
MetabolomicsBio-organic fertilizer alleviates tobacco continuous cropping obstacles by coordinately reprogramming plant metabolism and the rhizosphere microbiome
Background Crop continuous cropping obstacles (CCO) severely threaten soil ecosystem health and sustainable agricultural production. Although bio-organic fertilizer (BF) has been widely applied to mitigate crop CCO, the underlying mechanisms remain poorly understood. Herein, an Aspergillus-amended B...
2026-04-13 | MTBLS14267 | MetaboLights
TranscriptomicsTranscriptome alterations associated with TMV-resistance in transgenic tobacco plants expressing the genomic RNA of the virus
Agilent 4x44k tobacco micro array of wild type tobacco (WT) and whole tobacco mosaic virus (TMV) containing transgenic tobacco plants. The transgenic plants before resistance break (BRB-6 weeks), after resistance break (ARB-8 weeks) and wild type tobacco plants infected with TMV (TMVi-9weeks) leaves...
ORGANISM(S): Nicotiana tabacum 
2014-11-03 | E-MEXP-3934 | biostudies-arrayexpress
MetabolomicsNavigating natural variation in herbivory-induced secondary metabolism in coyote tobacco populations using MS/MS structural analysis
Natural variation can be extremely useful in unraveling the determinants of phenotypic trait evolution but has rarely been analyzed with unbiased metabolic profiling to understand how its effects are organized at the level of biochemical pathways. Native populations of Nicotiana attenuata, a wild to...
2015-06-15 | MTBLS203 | MetaboLights
MetabolomicsSimilar, but different: structurally related azelaic acid and hexanoic acid trigger differential metabolomic and transcriptomic responses in tobacco cells
BACKGROUND: Plants respond to various stress stimuli by activating an enhanced broad-spectrum defensive ability. The development of novel resistance inducers represents an attractive, alternative crop protection strategy. In this regard, hexanoic acid (Hxa, a chemical elicitor) and azelaic acid (Aza...
2018-10-17 | MTBLS559 | MetaboLights
MetabolomicsMulti-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke
Cigarette smoke (CS) causes adverse health effects and leads to the development of respiratory disease (chronic obstructive pulmonary disease), cardiovascular disease, and cancer. To reduce the risk of smokers developing smoking-related diseases, Philip Morris International is developing modified ri...
2020-04-25 | MTBLS158 | MetaboLights
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