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TranscriptomicsTranscription profiling of mouse model for ETV6-NTRK3 (EN) fusion oncoprotein expresson
We report a mouse model that recapitulates expression of the ETV6-NTRK3 (EN) fusion oncoprotein, the product of the t(12;15)(p13;q25) translocation characteristic of human secretory breast carcinoma. Activation of EN expression in mammary tissues by Whey acidic protein (Wap) promoter-driven Cre lead...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9353 | biostudies-arrayexpress
ProteomicsEvaluation of differential peptide loading on TMT-based proteomic and phosphoproteomic data quality
Investigating the impacts on MS data quantitation reproducibility when loading differential amounts of peptides, ranging from 20 to 400 ug, across channels of TMT 11 multiplexes. PTRC_Exp9 files represent global proteome and phosphoproteome data generated from PBMCs isolated from AML patients, acqui...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-05 | MSV000086417 | MassIVE
TranscriptomicsTranscription profiling of mouse mammary tumours developed in Wap-Cre;Etv6-NTRK3 mice
We report a mouse model that recapitulates expression of the ETV6-NTRK3 (EN) fusion oncoprotein, the product of the t(12;15)(p13;q25) translocation characteristic of human secretory breast carcinoma. Activation of EN expression in mammary tissues by Whey acidic protein (Wap) promoter-driven Cre lead...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9355 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse model that recapitulates the ETV6-NTRK3 fusion oncoprotein the product of the t(12;15)(p13;q25) translocation characteristic of human secretory breast carcinoma
We report a mouse model that recapitulates expression of the ETV6-NTRK3 (EN) fusion oncoprotein, the product of the t(12;15)(p13;q25) translocation characteristic of human secretory breast carcinoma. Activation of EN expression in mammary tissues by Whey acidic protein (Wap) promoter-driven Cre lead...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9354 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mammary tissues from mouse model of breast cancer conditionally expressing Etv6-NTRK3 (EN) fusion oncoprotein, the product of the t(12;15)(p13;q25) translocation
For the largest class of human tumors, those of epithelial origin, little is known about their initiating genetic hits or cells of origin. Whether tissue stem cells or more committed progenitors are targets for transformation is also uncertain. Experience in hematopoietic malignancies and sarcomas ...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9343 | biostudies-arrayexpress
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