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Results of an open-label phase 1b study of the ERK inhibitor MK-8353 plus the MEK inhibitor selumetinib in patients with advanced or metastatic solid tumors.
Not available
S-EPMC10289957
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biostudies-literature
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A phase 1 dose escalation and expansion study of Tarextumab (OMP-59R5) in patients with solid tumors.
Not available
S-EPMC6647865
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biostudies-literature
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Changes of lung tumour volume on CT - prediction of the reliability of assessments.
Not available
S-EPMC4628325
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biostudies-literature
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A phase 1 study of the BCL2-targeted deoxyribonucleic acid inhibitor (DNAi) PNT2258 in patients with advanced solid tumors.
Not available
S-EPMC3909249
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biostudies-literature
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A First-in-Human Phase I Study of OPB-111077, a Small-Molecule STAT3 and Oxidative Phosphorylation Inhibitor, in Patients with Advanced Cancers.
Not available
S-EPMC6067949
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biostudies-literature
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TIGIT inhibitor M6223 as monotherapy or in combination with bintrafusp alfa in patients with advanced solid tumors: a first-in-human, phase 1, dose-escalation trial.
Not available
S-EPMC11815413
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biostudies-literature
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The future of cytotoxic therapy: selective cytotoxicity based on biology is the key.
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S-EPMC165009
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A single supratherapeutic dose of ridaforolimus does not prolong the QTc interval in patients with advanced cancer.
Not available
S-EPMC3456920
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A First-in-Human Study of ATM Inhibitor Lartesertib as Monotherapy in Patients with Advanced Solid Tumors.
Not available
S-EPMC12580772
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biostudies-literature
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A phase 1 study of anti-TGFβ receptor type-II monoclonal antibody LY3022859 in patients with advanced solid tumors.
Not available
S-EPMC5893148
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