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TranscriptomicsExpression data from CD4+ NaM-CM-/ve T cells under Treg-inducing condition in the presence or absence of butyrate
Commensal bacteria shapes gut immune system. Colonization bacteria increase the frequency of regulatory T cells, however, the molecular mechanisms has not yet been unknown. To reveal the mechanism, we isolated NaM-CM-/ve CD4+ T cells from spleen of C57BL/6 mice and cultured the cells under Treg-indu...
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-49619 | biostudies-arrayexpress
GenomicsCommensal microbe-derived butyrate epigenetically induces colonic regulatory T cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-49655 | biostudies-arrayexpress
GenomicsGenome-wide measurement of acetylated histone H3 in naïve cells under Treg-inducing conditon
To investigate the molecular mechanism how butyrate promoter differentiation of naïve T cells into regulatory T cells Examination of acetylated histone H3 during the differentiation of regulatory T cells in the presence or absence of butyrate
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-49653 | biostudies-arrayexpress
UnknownBCG vaccine may generate cross-reactive T cells against SARS-CoV-2: In silico analyses and a hypothesis.
Not available
S-EPMC7440160 | biostudies-literature
UnknownLive-bearing without placenta: Physical estimation indicates the high oxygen-supplying ability of white shark uterus to the embryo.
Not available
S-EPMC5603572 | biostudies-literature
UnknownRegulatory T cells Are Increased and Correlate With Mast Cells in Eosinophilic Esophagitis.
Not available
S-EPMC10774801 | biostudies-literature
MetabolomicsMetabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival

The spread of cancer to bone is invariably fatal, with complex cross-talk between tumor cells and the bone microenvironment responsible for driving disease progression. By combining in silico analysis of patient datasets with metabolomic profiling of prostate cancer cells cultured with bone cells...

2024-08-19 | MTBLS3973 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
UnknownClinical Implications and Molecular Characterization of Drebrin-Positive, Tumor-Infiltrating Exhausted T Cells in Lung Cancer.
Not available
S-EPMC9694580 | biostudies-literature
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAD targeted time-course)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7253 | MetaboLights
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