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TranscriptomicsHigh weight differences between donor and recipient affect early kidney graft function -a role for IL-6 signaling
The frequency of delayed function of kidney transplants varies greatly and is associated with the quality of graft, donor age, and the duration of cold ischemia time. Body weight differences between donor and recipient can affect primary graft function. The underlying mechanism is poorly understood....
ORGANISM(S): Rattus norvegicus 
2010-04-08 | E-GEOD-15813 | biostudies-arrayexpress
TranscriptomicsIndices of Tolerance (IOT): Cross-platform biomarkers that identify kidney transplant tolerance
Being able to identify patients in whom immunological tolerance has been established or is developing would allow an individually tailored approach to post-transplant management of kidney allograft recipients. Ex vivo immunological monitoring was performed on samples from five groups of European ren...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-14655 | biostudies-arrayexpress
TranscriptomicsImmunomagnetic purification of mES derived neuronal precursors increases neuronal migration and differentiation in vivo
All established protocols for differentiation of mouse and human pluripotent stem cells into specific neural subpopulations generate a considerable cellular heterogeneity that hampers experimental and clinical progress. In order to obtain a homogenous population of neuronal precursor cells and to st...
ORGANISM(S): Mus musculus 
2013-12-21 | E-GEOD-35125 | biostudies-arrayexpress
TranscriptomicsInterleukin-10-anergized T-cell infusion provides immune reconstitution without severe graft-versus-host disease after haploidentical hematopoietic stem cell transplantation
Regulatory T cells restore tolerance in preclinical models of immune-mediated diseases and are therefore a promising alternative to conventional immune-suppression for preventing graft-versus-host disease (GvHD) in patients receiving allogeneic hematopoietic stem cell transplantation (HSCT). Adaptiv...
ORGANISM(S): Homo sapiens 
2015-12-14 | E-GEOD-21885 | biostudies-arrayexpress
TranscriptomicsPurification of neuronal precursors from the adult mouse brain: a comprehensive gene expression analysis
The progeny of neural stem cells in the subventricular zone (SVZ) of the adult mammalian brain consists in polysialylated NCAM-expressing immature neurons (PSA(+) cells), which migrate to the olfactory bulb (OB) to differentiate into GABAergic interneurons. We purified murine PSA(+) cells directly f...
ORGANISM(S): Mus musculus 
2007-09-21 | E-GEOD-9081 | biostudies-arrayexpress
TranscriptomicsSca-1 expression defines different developmental stages of mouse PDC that show functional heterogeneity in the endosomal but not lysosomal TLR9 response
Plasmacytoid dendritic cells (PDC) play an important role in innate and adaptive immunity and were shown to be identical to previously described natural IFN-M-NM-1-producing cells (NIP). Here, we describe two functionally distinct PDC subpopulations that are characterized by the differential express...
ORGANISM(S): Mus musculus 
2013-12-21 | E-GEOD-42860 | biostudies-arrayexpress
TranscriptomicsSSEA4 is a marker for chemotherapy resistance
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-11-19 | E-GEOD-57705 | biostudies-arrayexpress
TranscriptomicsAntibody-based selective isolation of atrial and ventricular cardiomyocytes by differential expression of integrin α6 (CD49f)
Central questions like cardiomyocyte subtype emergence during cardiogenesis or availability of cardiomyocyte subtypes for cell replacement therapy require selective identification and purification of atrial and ventricular cardiomyocytes. However, characterization and implementation of pure cardiomy...
ORGANISM(S): Mus musculus 
2015-12-14 | E-GEOD-57131 | biostudies-arrayexpress
UnknownCloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?
Not available
S-EPMC19888 | biostudies-literature
UnknownImmunological Outcome in Haploidentical-HSC Transplanted Patients Treated with IL-10-Anergized Donor T Cells.
Not available
S-EPMC3907718 | biostudies-literature
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