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ProteomicsReference proteome of highly purified human Th1 cells reveals strong effects on metabolism and protein ubiquitination upon differentiation
The differentiation of human CD4+ T cells into different subtypes of T helper cells and regulatory T cells is crucial for an appropriate immunological response. Among all subtypes Th1 cells are the most prominent specific cell type, representing about 50% of all lymphocytes. So far most global prote...
ORGANISM(S): Homo sapiens (Human) 
2015-10-13 | PXD001066 | Pride
Th1 cells Cd4+ Human Lc-ms/ms 
ProteomicsCompartment resolved reference map from highly purified naive, activated, effector and memory CD8+ cells
Differentiation of CD8+ T lymphocytes into effector and memory cells is key for an adequate immune response and relies on complex interplay of pathways that convey signals from cell surface to nucleus. In this study, we fractionated four CD8+ T cell subtypes; naïve, recently activated effector, effe...
ORGANISM(S): Mus musculus (Mouse) 
2015-02-04 | PXD001065 | Pride
Murine Cd8+ Lc-ms/ms 
ProteomicsCompartment resolved reference map from highly purified naive, activated, effector and memory CD8+ cells
Differentiation of CD8+ T lymphocytes into effector and memory cells is key for an adequate immune response and relies on complex interplay of pathways that convey signals from cell surface to nucleus. In this study, we fractionated four CD8+ T cell subtypes; naïve, recently activated effector, eff...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-02-29 | MSV000079540 | MassIVE
TranscriptomicsmiRNA expression, mRNA expression upon miRNA reconstitution, and direct mRNA target identification in prostate cancer cell lines
This SuperSeries is composed of the following subset Series: GSE17315: mRNA expression upon reconstitution of miR-130a, miR-203 and miR-205 in prostate cancer cell line LNCaP GSE17317: miRNA expression in LNCaP, PC3, Du-145 and RWPE-1 cell lines GSE22979: Profiling of direct mRNA targets of miR-130a...
ORGANISM(S): Homo sapiens 
2012-03-07 | E-GEOD-17362 | biostudies-arrayexpress
TranscriptomicsProfiling of direct mRNA targets of miR-130a, miR-203 and miR-205 in prostate cancer cell line LNCaP
Micro RNAs (miRNAs) miR-130a, miR-203 and miR-205 are jointly downregulated in prostate cancer and act as repressors of AR-signaling. MiRNAs are small non-coding RNAs that regulate the expression of specific mRNA targets mainly by translational repression, mRNA deadenylation or cleavage. Reconstitu...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-22979 | biostudies-arrayexpress
TranscriptomicsmRNA expression upon reconstitution of miR-130a, miR-203 and miR-205 in prostate cancer cell line LNCaP
Micro RNAs (miRNAs) miR-130a, miR-203 and miR-205 are jointly downregulated in prostate cancer and act as repressors of AR-signaling. MiRNAs are small non-coding RNAs that regulate the expression of specific mRNA targets mainly by translational repression, mRNA deadenylation or cleavage. Reconstitu...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-17315 | biostudies-arrayexpress
TranscriptomicsmiRNA expression in LNCaP, PC3, Du-145 and RWPE-1 cell lines
MiRNAs are small non-coding RNAs that regulate the expression of specific mRNA targets mainly by translational repression, mRNA deadenylation or cleavage. This series is meant to identify miRNAs deregulated in prostate cancer (PCa) by comparing the PCa cell lines LNCaP, PC3 and Du-145 to the normal ...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-17317 | biostudies-arrayexpress
OtherCompartment resolved reference proteome map from highly purified na-ve, activated, effector, and memory CD8+ murine immune cells.
Data from ProteomeXchange, PXD ID: PXD001065. Experiment: Aus7, file: Aus7_35.mzml. Published as part of Proteomics. 2015 Jan 23 . From the Abstract: {{i}} In this study, we investigated the proteome of four cytotoxic T cell subtypes; na-ve, recently activated effector, effector and memory cells. C...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32310006565 | GPMDB
Resource Reanalysis 
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