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UnknownElevated Lactate Dehydrogenase (LDH) level as an independent risk factor for the severity and mortality of COVID-19.
Not available
S-EPMC7467395 | biostudies-literature
UnknownChronic Cardio-Metabolic Disease Increases the Risk of Worse Outcomes Among Hospitalized Patients With COVID-19: A Multicenter, Retrospective, and Real-World Study.
Not available
S-EPMC8477891 | biostudies-literature
MetabolomicsNMR-based metabonomics and correlative analysis reveals potential bomarkers associated with chronic atrophic gastritis
Chronic atrophic gastritis (CAG) is one of the most important pre-cancerous states with a high prevalence. Exploring of the underlying mechanism and potential biomarkers is of significant importance for CAG. In the present work, 1H NMR-based metabonomics with correlative analysis was performed to an...
2016-08-31 | MTBLS340 | MetaboLights
ProteomicsOverexpress S-protein tagged mouse TBK1 protein and identify the TBK1-interacting proteins by mass spectrometry
HEK293T cells were transfected with SFB-tagged mTBK1 or an empty vector for 24 h, the cells were lysed with lysis buffer (20 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5% Triton X-100, 10% glycerol, 1 mM ethylenediaminetetraacetic acid) containing a complete protease inhibitor cocktail, followed by centrif...
ORGANISM(S): Homo Sapiens Mus Musculus 
2023-10-27 | PXD045961 |
ProteomicsHypoxia Regulates Overall mRNA Homeostasis by Inducing Met1-linked Linear Ubiquitination of AGO2 in Cancer Cells
Hypoxia is the most prominent feature in human solid tumors and induces activation of hypoxia-inducible factors and their downstream genes to promote cancer progression. However, whether and how hypoxia regulates overall mRNA homeostasis is unclear. Here we show that hypoxia inhibits global-mRNA dec...
ORGANISM(S): Homo Sapiens 
2021-04-06 | PXD021722 |
ProteomicsQuantitative proteomics profilling of p62 droplet
Phase separated p62 body plays pivotal roles during autophagosome formation, however, the underlying mechanisms are still not fully understood. Mass spectrometry-based proteomics revealed significant enrichment of vesicle trafficking components within p62 bodies.
ORGANISM(S): Homo Sapiens Rattus Norvegicus 
2023-06-09 | PXD038262 |
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