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The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is limited. Here we present high-resolution analyses of chromosomal organization in pluripotent and differentiated human and murine cell types determined u...
ORGANISM(S): Mus musculus 
Regions of very low H3K27me3 partition the Drosophila genome into topological domains
Conserved Topological Domains in Mammalian Genomes Identified by High-resolution Analysis of Chromatin Interactions
Setdb1 regulates Cohesin at H3K9me3-independent topological domains
The three-dimensional (3D) organization of the genome within the cell nucleus contributes to cell-specific gene expression in different cell types1. High-throughput 3CM-bM-^@M-^Sderived methods have revealed that the genome is segmented into contiguous topologically associating domains (TADs), which...
ORGANISM(S): Homo sapiens 
Epigenetic maintenance of topological domains in the rearranged gibbon genome [WBGS]
Setdb1 regulates Cohesin at H3K9me3-independent topological domains [Hi-C]
Epigenetic maintenance of topological domains in the rearranged gibbon genome
Setdb1 regulates Cohesin at H3K9me3-independent topological domains [RNA-Seq]
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