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UnknownWhole genome shotgun sequences of Streptococcus pyogenes causing acute pharyngitis from India.
Not available
S-EPMC5996613 | biostudies-literature
TranscriptomicsCRISPR screen exploring resistance to AKTi (Capivasertib) in ER+ Breast Cancer in MCF7, T47D and CAMA-1 cell lines
A genome-wide CRISPR-Cas9 knockout screen was performed in the breast cancer cell lines T47D, MCF7, and CAMA-1 to identify genes modulating sensitivity and resistance to capivasertib, a selective AKT inhibitor. Cells were transduced with a CRISPR library, followed by treatment with capivasertib or v...
ORGANISM(S): Homo sapiens 
2026-05-25 | E-MTAB-16438 | biostudies-arrayexpress
TranscriptomicsEffect of Estrogen Receptor Beta Ligand on Gene Expression in White Adipose Tissue
C57BL/6 male mice were fed with normal diet or high fat diet and treated with vehicle or 30 mg/kg/day s.c. of ER-beta ligand, B-LGND2. Genes differentially expressed by H.F.D. and B-LGND2 are represented in this RNA-Sequencing data n=3/group. White adipose tissue. Mice were fed and treated as indica...
ORGANISM(S): Mus musculus 
2016-08-15 | E-GEOD-85498 | biostudies-arrayexpress
TranscriptomicsNurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons
Nurr1 (Nr4a2, nuclear receptor subfamily 4 group A member 2) is needed for the development of ventral midbrain dopaminergic neurons, and has been associated with Parkinson's disease. We used mice where the Nurr1 gene is ablated by tamoxifen treatment selectively in dopaminergic neurons. As a control...
ORGANISM(S): Mus musculus 
2013-01-14 | E-GEOD-42912 | biostudies-arrayexpress
TranscriptomicsDiverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells (Affymetrix)
The effects of diverse stresses on promoter selectivity and transcription regulation by the tumor suppressor p53 are poorly understood. We have taken a comprehensive approach to characterizing the human p53 network that includes p53 levels, binding, expression and chromatin changes under diverse str...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-46493 | biostudies-arrayexpress
TranscriptomicsEarly life growth and gene profile changes during childhood
To compare early life exposures to see if they are associated with persistent molecular changes at the transcriptional level. Subjects were drawn from the Newcastle Pre-Term Birth Growth Study. A randomised, controlled trial to look at the effect on growth of dietary manipulation after hospital dis...
ORGANISM(S): Homo sapiens 
2012-03-14 | E-GEOD-22013 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of the newly described centipede Eupolybothrus cavernicolus sp.n.
We compiled the transcriptome by extracting mRNA, reverse transcription and Illumina sequencing, followed by assembly and annotation by comparison with public databases (including; Nr, SwissProt and COG). Quantitative data on the transcription abundance of each putative protein sequence is provided ...
ORGANISM(S): Eupolybothrus sp. PS-2013 
2013-10-28 | E-MTAB-1859 | biostudies-arrayexpress
GenomicsDNA Methylation Analysis of Prostate Cancer Cell Lines and Tissues Using Next Generation Sequencing

Aberrant DNA methylation changes are known to occur during prostate cancer progression beginning with precursor lesions. Utilizing fifty nanograms of genomic DNA in Methylplex-Next Generation Sequencing (M-NGS) we mapped the global DNA methylation patterns in prostate tissues (n=17) and cells (n=...

phs000597.v1.p1 | EGA
GenomicsGeneration of chromatin maps for ASH1 and FSH applying ChIP-seq
see Super Series Summary Cross-linked chromatin derived from Drosophila S2-DRSC cells was immunoprecipitated using antibodies targeting ASH1 and FSH. Precipitated chromatin was sequenced applying Illumina sequencing.
ORGANISM(S): Drosophila melanogaster 
2013-02-06 | E-GEOD-36404 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing of transgenic Arabidopsis seedlings constitutively expressing a Colletotrichum higginsianum effector
The fungal pathogen Colletotrichum higginsianum secretes effector proteins during infection of Arabidopsis. To explore the host processes perturbed by the effector candidate ChEC108 in host plants, transgenic Arabidopsis lines were generated to express AtUBQ10pro:ChEC108-eGFP or AtUBQ10pro:ChEC108^D...
ORGANISM(S): Arabidopsis thaliana 
2026-05-21 | E-MTAB-16996 | biostudies-arrayexpress
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