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MetabolomicsN6-methyladenosine modification is not a general trait of positive-sense RNA viral genomes

Despite the nuclear localization of the m6A machinery, the genomes of multiple exclusively-cytoplasmic RNA viruses, such as chikungunya (CHIKV) and dengue (DENV), are reported to be extensively m6A-modified. However, these findings are mostly based on m6A-seq, an antibody-dependent technique with...

2024-01-25 | MTBLS6978 | MetaboLights
ProteomicsGlycosylation profiling of Influenza A Virus H3 HA
The quest for a universal influenza vaccine holds great promise for mitigating the global burden of influenza-related morbidity and mortality. Despite significant progress, challenges persist in identifying conserved epitopes capable of inducing broadly protective immune responses, understanding the...
ORGANISM(S): Influenza A virus 
2026-01-12 | PXD051492 | Pride
Glycosylation  influenza 
UnknownHydroxylamine Derivatives as a New Paradigm in the Search of Antibacterial Agents.
Not available
S-EPMC6643834 | biostudies-literature
UnknownNew Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action.
Not available
S-EPMC6348444 | biostudies-literature
UnknownDrug-Free Enzyme-Based Bactericidal Nanomotors against Pathogenic Bacteria.
Not available
S-EPMC8478280 | biostudies-literature
UnknownImpact of mindfulness on football coaches: A mixed design.
Not available
S-EPMC11449272 | biostudies-literature
UnknownVaccine Hesitancy Among General Practitioners and Its Determinants During Controversies: A National Cross-sectional Survey in France.
Not available
S-EPMC4563133 | biostudies-literature
TranscriptomicsCytokine-independent detection of antigen-specific germinal center T follicular helper (Tfh) cells in immunized non-human primates using a live cell Activation Induced Marker (AIM) technique
A range of current candidate AIDS vaccine regimens are focused on generating protective HIV neutralizing antibody responses. Many of these efforts rely on the rhesus macaque animal model. Understanding how protective antibody responses develop and how to increase their efficacy are both major knowle...
ORGANISM(S): Macaca mulatta 
2016-09-07 | E-GEOD-81382 | biostudies-arrayexpress
UnknownFrom Clinging to Digging: The Postembryonic Skeletal Ontogeny of the Indian Purple Frog, Nasikabatrachus sahyadrensis (Anura: Nasikabatrachidae).
Not available
S-EPMC4814056 | biostudies-literature
GenomicsA comprehensive assessment of somatic mutation detection in cancer using whole genome sequencing
As whole genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Using tumor-normal sample pairs from two different types of cancer, chronic lymphocytic leukemia and medulloblastoma, we conducted a ...
EGAS00001001539 | EGA
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