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MetabolomicsIonomic, Metabolomic, and Enzymatic Responses of the Sea Cucumber Apostichopus japonicus to Single and Combined Salinity and Metal Stress

Desalination brine discharge poses emerging threats to benthic marine organisms through combined salinity stress and metal contamination. This study investigated the individual and combined effects of salinity (35 ppt) and metal exposure (Cu, Fe, and Cd) on the sea cucumber Apostichopus japonicus...

2026-03-18 | MTBLS14079 | MetaboLights
Transcriptomicsmetal stress 2
Effect of mild metal ion - stress (500µM AlCl3, 500µM VCl3, 1.5mM ZnCl2) on cellular metabolism, resp. on transcription - 30min incubation in yeast Saccharomyces cerevisiae (JSwt - is a FY derivate; MATaleu2ura3trp1HIS3)
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-01 | E-MEXP-2987 | biostudies-arrayexpress
Transcriptomicsmetal stress 1
Effect of mild metal ion-stress (40µM AgNO3, 200µM AsCl3, 2µM CdCl2, 100µM CoCl2, 30µM HgCl2, 1.5mM MnCl2, 1.5mM NiSO4) on cellular metabolism, resp. on transcription - 30min incubation in yeast Saccharomyces cerevisiae
ORGANISM(S): Saccharomyces cerevisiae 
2011-01-01 | E-MEXP-2985 | biostudies-arrayexpress
TranscriptomicsHeavy metal resistance in Cupriavidus metallidurans CH34 is governed by an intricate transcriptional network.
Background: The high number of heavy metal resistance genes in the soil bacterium Cupriavidus metallidurans CH34 makes it an interesting model organism to study microbial responses to heavy metals. Results: In this study the transcriptional response of this bacterium was measured after challenging i...
ORGANISM(S): Cupriavidus metallidurans CH34 
2011-06-28 | E-GEOD-23876 | biostudies-arrayexpress
TranscriptomicsSalmonella response to copper and zinc
Salmonella can infect a wide range of hosts and survive in the environment. This invasive pathogen has therefore evolved and acquired specific traits to cope with different, and in most cases unfavorable, conditions. In particular, transition metal ions are widely spread in these niches. These ions ...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2012-03-15 | E-GEOD-35328 | biostudies-arrayexpress
TranscriptomicsNickel and binary metal mixtures in Daphnia magna after 96h
The recent development of a custom cDNA microarray platform for one of thé standard organisms in aquatic toxicology, Daphnia magna, opened up new ways to mechanistic insights of toxicological responses. In this study, gene expression and (sub)organismal responses (Cellular Energy Allocation, growt...
ORGANISM(S): Daphnia magna 
2010-05-22 | E-GEOD-13866 | biostudies-arrayexpress
GenomicsEpigenetic Dysregulation of H19/IGF2 in Hepatic Cells Exposed to Toxic Metal Mixtures In Vitro [RNA-seq]
Epigenetic Dysregulation of H19/IGF2 in Hepatic Cells Exposed to Toxic Metal Mixtures In Vitro [RNA-seq]
PRJNA1175981 | ENA
GenomicsEpigenetic Dysregulation of H19/IGF2 in Hepatic Cells Exposed to Toxic Metal Mixtures In Vitro [Bisulfite-seq]
Epigenetic Dysregulation of H19/IGF2 in Hepatic Cells Exposed to Toxic Metal Mixtures In Vitro [Bisulfite-seq]
PRJNA1175979 | ENA
TranscriptomicsEpigenetic Dysregulation of H19/IGF2 in Hepatic Cells Exposed to Toxic Metal Mixtures In Vitro [RNA-seq]
Exposure to mixtures of toxic metals is known to cause adverse health effects through epigenetic alterations. Here we aimed to examine the unexplored area of aberrant DNA methylation in the H19/IGF2 domain following combined toxic metal exposure. An in vitro epigenotoxicity assay using the human nor...
ORGANISM(S): Homo sapiens 
2024-10-27 | GSE280026 | GEO
Methylation profilingEpigenetic Dysregulation of H19/IGF2 in Hepatic Cells Exposed to Toxic Metal Mixtures In Vitro [Bisulfite-seq]
Exposure to mixtures of toxic metals is known to cause adverse health effects through epigenetic alterations. Here we aimed to examine the unexplored area of aberrant DNA methylation in the H19/IGF2 domain following combined toxic metal exposure. An in vitro epigenotoxicity assay using the human nor...
ORGANISM(S): Homo sapiens 
2024-10-27 | GSE280025 | GEO
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