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TranscriptomicsTranscription profiling by array of Nipponbare rice roots over a time course of potassium deprivation
Potassium (K+) is one of the most important nutrient ions in plant cells and play crucial roles in many plant physiological and developmental processes. K+ deficiency is the common abiotic stress in natural environment, which inhibits plant growth and reduces production of crops. We used microarrays...
ORGANISM(S): Oryza sativa japonica 
2012-10-31 | E-GEOD-37161 | biostudies-arrayexpress
TranscriptomicsGenome-scale reconstruction of the PurR regulon reveals its role in the adenine stimulon of Escherichia coli K-12 MG1655
This SuperSeries is composed of the following subset Series: GSE26588: Transcriptome analysis of E. coli MG1655 GSE26589: ChIP-chip of E. coli K-12 MG1655 with antibody against PurR-8myc under various conditions. Refer to individual Series
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2012-01-12 | E-GEOD-26591 | biostudies-arrayexpress
TranscriptomicsChIP-chip of E. coli K-12 MG1655 with antibody against PurR-8myc under various conditions.
We integrated transcription factor binding regions and mRNA transcript abundance to elucidate the PurR regulon experimentally. To measure transcription factor binding at a genome scale, we employed a ChIP-chip method to derivative strains of E. coli K-12 MG1655 harboring PurR-8myc under various con...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2011-06-14 | E-GEOD-26589 | biostudies-arrayexpress
TranscriptomicsHigh-fat diet-mediated dysbiosis cooperates with oncogenic K-Ras activation to promote intestinal carcinogenesis independently of obesity.
Several aspects of a Western lifestyle such as increased obesity and decreased physical activity are associated with increased risk for gastrointestinal cancers1. Although high-fat diet (HFD) induced low-grade inflammation has been closely linked to tumorigenesis2, however, the microbial shift that ...
ORGANISM(S): Mus musculus 
2013-07-01 | E-GEOD-42840 | biostudies-arrayexpress
GenomicsDecoding genome-wide GadEWX transcriptional regulatory networks reveals a multifaceted cellular response to acid stress in Escherichia coli [ChIP-seq]
The response to acid stress is a fundamental process in bacteria. Three transcription factors, GadE, GadW, and GadX (GadEWX) are known to play a critical role in the transcriptional regulation of glutamate-dependent acid resistance (GDAR) system in Escherichia coli K-12 MG1655. However, the regulato...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2015-08-11 | E-GEOD-66441 | biostudies-arrayexpress
ProteomicsThe natural statin α,β-dehydromonacolin K exerts anti-secretory effect in human intestinal epithelial cells via a nonsense-mediated mRNA decay-dependent mechanism
The cAMP-induced intestinal chloride secretion plays a significant role in the pathogenesis of secretory diarrheas. This study aimed to investigate the anti-secretory effects of α,β-dehydromonacolin K, a derivative of lovastatin from Aspergillus sclerotiorum, on cAMP-induced chloride and fluid secre...
ORGANISM(S): Homo Sapiens (human) 
2025-01-01 | PXD058025 | JPOST Repository
MetabolomicsAn Evolutionarily Conserved Metabolite Inhibits Biofilm Formation in Escherichia coli K-12
Methylerythritol cyclodiphosphate (MEcPP) is an intermediate in the biosynthesis of isoprenoids in plant plastids and in bacteria, and acts as a stress signal in plants. Here, we show that MEcPP regulates biofilm formation in Escherichia coli K-12 MG1655. Increased MEcPP levels, triggered by genetic...
2024-11-01 | MTBLS2240 | MetaboLights
TranscriptomicsTranscription profiling of E. coli K-12 wild type with R1drd19 biofilm vs wild type without R1drd19 biofilm
E. coli K-12 wild type strains gene expression in biofilm cells with R1drd19 relative to that in biofilm cells of E. coli K-12 wild type strains without R1drd19. All the samples were cultured in LB or M9C glu on glass wool at different time. Experiment Overall Design: Strains: E. coli K-12 strains ...
ORGANISM(S): Escherichia coli 
2008-04-05 | E-GEOD-6923 | biostudies-arrayexpress
TranscriptomicsDecoding genome-wide GadEWX transcriptional regulatory networks reveals a multifaceted cellular response to acid stress in Escherichia coli [RNA-seq]
The response to acid stress is a fundamental process in bacteria. Three transcription factors, GadE, GadW, and GadX (GadEWX) are known to play a critical role in the transcriptional regulation of glutamate-dependent acid resistance (GDAR) system in Escherichia coli K-12 MG1655. However, the regulato...
ORGANISM(S): Escherichia coli 
2015-08-11 | E-GEOD-66481 | biostudies-arrayexpress
UnknownComprehensive survey on the use of plastic additives in toy products used in Japan.
Not available
S-EPMC11362670 | biostudies-literature
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