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MetabolomicsBasic Metabolism Studies (wt and TPA null)
Not available
ORGANISM(S): Mus musculus 
ST000160 | MetabolomicsWorkbench
TranscriptomicsDysregulation of pathways involved in the processing of cancer and microenvironment information in MCA+TPA transformed C3H/10T1/2 cells
The two-stage cell transformation assay is an in vitro model cell culture system to identify the ability of chemicals to act as initiators or promoters of cell transforma- tion and also to study the cellular and molecular mechanisms of chemically induced morphological and neoplastic cell transformat...
ORGANISM(S): Mus musculus 
2013-04-26 | E-GEOD-41142 | biostudies-arrayexpress
GenomicsRegulation of Megakaryocytic differentiation in Cell Line Models by Dynamic Combinatorial Interactions of RUNX1 with Its Cooperating Partners
Regulation of Megakaryocytic differentiation in Cell Line Models by Dynamic Combinatorial Interactions of RUNX1 with Its Cooperating Partners Examination of RUNX1 binding in K562 cells, before and following TPA induction and CMK cells. Examination of GATA1 and FOS binding and H3K4me1 and H3K27me3 mo...
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-24777 | biostudies-arrayexpress
TranscriptomicsDifferent response of WT and Ts keratinocyte to TPA treatment
Ts keratinocyte has increased proliferation compare to WT keratinocyte upon TPA treatment. This result showed the different transcription regulation in Ts and WT keratinocyte upon TPA treatment. Total RNA extracted from WT or Ts keratinocytes, not treated or treated with TPA for 12 hours.
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-40382 | biostudies-arrayexpress
TranscriptomicsExpression profiles of human primary keratinocytes differentiated with TPA
Human primary keratinocytes were left untreated or treated for 48 hr with 12-O-tetradecanoylphorbol-13-acetate (TPA) and expression profiles were compared to find long ncRNAs expressed and differentially regulated upon differentiation. 4 replicates of minus TPA and 3 of plus TPA with dye-swap. Custo...
ORGANISM(S): Homo sapiens 
2011-04-12 | E-GEOD-28552 | biostudies-arrayexpress
TranscriptomicsDynamic combinatorial interactions of RUNX1 and cooperating partners regulates megakaryocytic differentiation in cell line models
This SuperSeries is composed of the following subset Series: GSE24777: Regulation of Megakaryocytic differentiation in Cell Line Models by Dynamic Combinatorial Interactions of RUNX1 with Its Cooperating Partners GSE24778: Expresssion data in K562 cells, before and after TPA induction and including ...
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-24779 | biostudies-arrayexpress
TranscriptomicsDeletion of DUSP5 affects the expression of a subset of TPA-inducible genes
This experiment was designed to determine if deletion of the dual-specificity MAP kinase phosphatase encoded by DUSP5 had any effect on the pattern of gene expression in cells treated with the phorbol ester tumour promoter TPA. Sex matched primary WT and DUSP5 knockout MEFs were isolated from litter...
ORGANISM(S): Mus musculus 
2014-10-17 | E-GEOD-62433 | biostudies-arrayexpress
TranscriptomicsExpresssion data in K562 cells, before and after TPA induction and including a RUNX1 knockout construct or a control structure
Expresssion data in K562 cells, before and after TPA induction and including a RUNX1 knockout construct or a control structure Examination of gene expression in K562 cells, before and following TPA induction and with or without a RUNX1 KO construct or control
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-24778 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis between WT and tPA KO mice 4 weeks after overexpression of human alpha-synuclein in the substantia nigra
The goal of this study is to compare gene expression differences between WT and tPA KO mice 4 weeks after overexpression of human alpha-synuclein in the substantia nigra
ORGANISM(S): Mus musculus 
2022-03-28 | E-MTAB-11567 | biostudies-arrayexpress
TranscriptomicsMicroarray profiling of monocytic differentiaion reveals miRNA-mRNA intrinsic correlation (gene expression)
Since the expression profile of miRNAs is specific in different tissues or under different physiological conditions, the correlations between miRNAs and mRNAs could vary under different biological circumstances. This is a study also used expression profiles of miRNA and mRNA during monocytic differe...
ORGANISM(S): Homo sapiens 
2012-02-02 | E-GEOD-26377 | biostudies-arrayexpress
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