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UnknownEndolysosomal TPCs regulate social behavior by controlling oxytocin secretion.
Not available
S-EPMC9963339 | biostudies-literature
UnknownTPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP.
Not available
S-EPMC2867333 | biostudies-literature
TranscriptomicsLoss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells
Lung squamous cell carcinoma (SCC) is a deadly disease for which current treatments are inadequate. We demonstrate that bi-allelic inactivation of Lkb1 and Pten in the mouse lung led to SCC that recapitulated the histology, gene expression and microenvironment found in human disease. Lkb1/Pten-null ...
ORGANISM(S): Mus musculus 
2014-01-24 | E-GEOD-54351 | biostudies-arrayexpress
UnknownBoth RyRs and TPCs are required for NAADP-induced intracellular Ca²⁺ release.
Not available
S-EPMC4539342 | biostudies-literature
UnknownTelepharmacy Consultations (TPCs) in Local Pharmacies-A Bi-Centric Survey of Customer Opinions.
Not available
S-EPMC12736953 | biostudies-literature
ProteomicsFLAG-TCF21 interactome in HCT116 and TPCs by IP-MS
This project presents the proteomic profiling of protein complexes associated with the transcription factor TCF21, achieved through affinity purification coupled with mass spectrometry (AP-MS). The study aimed to comprehensively map the TCF21 interactome in two distinct cellular models: the human co...
ORGANISM(S): Homo Sapiens 
2025-12-12 | PXD071976 |
TranscriptomicsIdentification and targeting of long-term tumor propagating cells in small cell lung cancer
FACS sorted TPCs (CD24HighCD44LowEpCAMHigh) and non-TPCs (CD24Low, CD24HighCD44High, and CD24HighCD44LowEpCAMLow) from mouse primary SCLC tumors We used microarrays to identify genes that are differentially expressed in TPCs versus non-TPCs.
ORGANISM(S): Mus musculus 
2016-06-15 | GSE72406 | GEO
TranscriptomicsIdentification and targeting of long-term tumor propagating cells in small cell lung cancer
FACS sorted TPCs (CD24HighCD44LowEpCAMHigh) and non-TPCs (CD24Low, CD24HighCD44High, and CD24HighCD44LowEpCAMLow) from mouse primary SCLC tumors We used microarrays to identify genes that are differentially expressed in TPCs versus non-TPCs. Tumors isolated and dissociated from the mouse SCLC pre-cl...
ORGANISM(S): Mus musculus 
2016-06-15 | E-GEOD-72406 | biostudies-arrayexpress
TranscriptomicsExpression profiling of lung adenocarcinoma TPC tumor cells in Kras-driven NSCLC mouse model
Sustained tumor progression has been attributed to a distinct population of tumor-propagating cells (TPCs). To identify TPCs relevant to lung cancer pathogenesis, we investigated functional heterogeneity in tumor cells isolated from Kras-driven mouse models of non-small cell lung cancer (NSCLC). CD2...
ORGANISM(S): Mus musculus 
2013-07-08 | GSE46439 | GEO
TranscriptomicsExpression profiling of CD24+ and CD24- tumor cells in Kras-driven NSCLC mouse model
Sustained tumor progression has been attributed to a distinct population of tumor-propagating cells (TPCs). To identify TPCs relevant to lung cancer pathogenesis, we investigated functional heterogeneity in tumor cells isolated from Kras-driven mouse models of non-small cell lung cancer (NSCLC). CD2...
ORGANISM(S): Mus musculus 
2013-07-08 | GSE46438 | GEO
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