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ProteomicsProteolytic processing of CD99
The adhesion molecule CD99 is essential for transendothelial migration (TEM) of leukocytes. Here we demonstrate by biochemical and cellular assays that CD99 undergoes ectodomain shedding by the metalloprotease meprin ? and subsequent intramembrane proteolysis by ?-secretase. The cleavage site in CD9...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080746 | MassIVE
GenomicsTransendothelial migration of human B cells: chemokine versus antigen
Transendothelial migration of human B cells: chemokine versus antigen
PRJNA993633 | ENA
TranscriptomicsTranscription profiling of human PC-3-derived cell lines after transendothelial migration in vitro
Metastatic colonization involves cancer cell lodgment or adherence in the microvasculature and subsequent migration of those cells across the endothelium into a secondary organ site. To study this process further, we analyzed transendothelial migration of human PC-3 prostate cancer cells in vitro. ...
ORGANISM(S): Homo sapiens 
2009-01-25 | E-GEOD-14405 | biostudies-arrayexpress
TranscriptomicsS100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133A]
Pancreatic cancer is a devastating disease with both local invasion and distant metastasis. Identifying the genes expressed in liver metastases and signatures of metastatic progression would therefore be of particular importance as they could aid in both recurrence prediction as well as representing...
ORGANISM(S): Homo sapiens 
2013-08-15 | E-GEOD-19279 | biostudies-arrayexpress
TranscriptomicsS100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133B]
Pancreatic cancer is a devastating disease with both local invasion and distant metastasis. Identifying the genes expressed in liver metastases and signatures of metastatic progression would therefore be of particular importance as they could aid in both recurrence prediction as well as representing...
ORGANISM(S): Homo sapiens 
2013-08-15 | E-GEOD-19280 | biostudies-arrayexpress
TranscriptomicsExpression profile of PC-3-derived cell lines after transendothelial migration
Metastatic colonization involves cancer cell lodgment or adherence in the microvasculature and subsequent migration of those cells across the endothelium into a secondary organ site. To study this process further, we analyzed transendothelial migration of human PC-3 prostate cancer cells in vitro. W...
ORGANISM(S): Homo sapiens 
2009-01-15 | GSE14405 | GEO
TranscriptomicsS100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133_Plus_2]
We and others have shown that S100P is highly upregulated during the progression of pancreatic cancer. We used microarrays to look at the target genes regulated by S100P in the pancreatic cancer cell line Panc1. Keywords: Gene overexpression We generated stable cell lines by introducing control vec...
ORGANISM(S): Homo sapiens 
2013-08-15 | E-GEOD-19278 | biostudies-arrayexpress
TranscriptomicsExpression profile of PC-3-derived cell lines from transendothelial migration or in vivo metastasis
Metastatic colonization involves cancer cell lodgment or adherence in the microvasculature and subsequent migration of those cells across the endothelium into a secondary organ site. To study this process further, we analyzed both in vitro and in vivo migration of human PC-3 prostate cancer cells . ...
ORGANISM(S): Homo sapiens 
2014-04-10 | E-GEOD-56410 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse T cell model to characterize transendothelial migration across lymphatics
Sphingosine 1-phosphate (S1P) influences T cell migration into and out of secondary lymphoid organs; however, its mechanism of action remains uncertain. Our previous research shows that agonism of the S1P receptor S1P1 inhibits the egress of T lymphocytes from the peripheral tissues into afferent ly...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9237 | biostudies-arrayexpress
UnknownMicrotubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells.
Not available
S-EPMC8218694 | biostudies-literature
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