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ProteomicsE-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/A9 release from neutrophils via transient gasdermin D pore formation
S100A8/A9 is a proinflammatory mediator released by myeloid cells during many acute and chronic inflammatory disorders. However, the precise mechanism of its release from the cytosolic compartment of neutrophils is still elusive. We report here that E-selectin-induced rapid S100A8/A9 release during ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-25 | PXD041652 | Pride
Neutrophile Inflammation Gasdermin d Transient pore formation 
UnknownIon-Induced Transient Potential Fluctuations Facilitate Pore Formation and Cation Transport through Lipid Membranes.
Not available
S-EPMC9801421 | biostudies-literature
TranscriptomicsThe temporal transcriptomic signature of cartilage formation
To study chondrogenesis, we used a chicken limb bud model: We used RNA sequencing, and examined the differences between gene expression patterns during cartilage formation in micromass cultures of embryonic limb bud-derived progenitors. We sequenced in triplicate at Day 0,1,2,3,4,6,10,15 and also fr...
ORGANISM(S): Gallus gallus 
2023-03-28 | E-MTAB-12770 | biostudies-arrayexpress
UnknownE-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation.
Not available
S-EPMC10681899 | biostudies-literature
UnknownFusion Pore Formation Observed during SNARE-Mediated Vesicle Fusion with Pore-Spanning Membranes.
Not available
S-EPMC7335915 | biostudies-literature
UnknownTRPV4 modulates substrate stiffness mechanosensing and transcellular pore formation in human Schlemm's canal cells.
Not available
S-EPMC12154856 | biostudies-literature
ProteomicsA Pandas complex adapted for piRNA-guided transposon silencing and heterochromatin formation, Panx-IP-MS
The repression of transposons by the Piwi-interacting RNA (piRNA) pathway is essential to protect animal germ cells. In Drosophila ovaries, Panoramix (Panx) enforces transcriptional silencing by binding to the target-engaged Piwi-piRNA complex, although the precise mechanisms by which this occurs re...
ORGANISM(S): Drosophila Melanogaster 
PXD014926 |
UnknownHigh Transmembrane Voltage Raised by Close Contact Initiates Fusion Pore.
Not available
S-EPMC5145871 | biostudies-literature
UnknownThe Antimicrobial Peptide Gramicidin S Enhances Membrane Adsorption and Ion Pore Formation Potency of Chemotherapy Drugs in Lipid Bilayers.
Not available
S-EPMC8067072 | biostudies-literature
UnknownThe assembly dynamics of the cytolytic pore toxin ClyA.
Not available
S-EPMC4347018 | biostudies-literature
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