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TranscriptomicsRadiation-induced gene translation profiles reveal tumor type and cancer specific components
The goal of this study was to compare the radiation-induced gene translation profiles generated from human tumor cell lines that are treated with radiation. Keywords: stimulus or stress design A panel of cell lines included 5 gliomas, 4 pancreatic carcinomas, 3 breast carcinomas and 2 non-small cell...
ORGANISM(S): Homo sapiens 
2010-07-20 | E-GEOD-10547 | biostudies-arrayexpress
ModelsHu2020 - E. coli translation model
This translation model consists of 274 biochemical reactions, including 119 reactions with non-linear kinetics. This mechanistic model accounts for the concentrations of mRNA, the ribosome, the different charged tRNAs, and the elongation factors Ts (EF-Ts) and Tu (EF-Tu). We fully parameterized the ...
2020-07-01 | MODEL2006210001 | BioModels
TranscriptomicsActivation of GCN2 by Ribosome Stalling Links Translation Elongation with Translation Initiation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-06-15 | E-GEOD-79930 | biostudies-arrayexpress
ProteomicsIn vitro synthesis of 32 translation-factor proteins from a single template reveals impaired ribosomal processivity
The Protein synthesis Using Recombinant Elements (PURE) system enables transcription and translation of a DNA template from purified components. Therefore, the PURE system-catalyzed generation of RNAs and proteins constituting the PURE system itself represents a major challenge toward a self-replica...
ORGANISM(S): Escherichia Coli 
2021-09-06 | PXD020877 | panorama
ModelsKong2022 - Conditional Antibody Design as 3D Equivariant Graph Translation
Multi-channel Equivariant Attention Network (MEAN) to co-design 1D sequences and 3D structures of CDRs. To be specific, MEAN formulates antibody design as a conditional graph translation problem by importing extra components including the target antigen and the light chain of the antibody. Then, MEA...
2023-05-10 | BIOMD0000001070 | BioModels
Machine Learning Model FAIR-AIML 
Genomicsp26 condensates from Pea enation mosaic virus 2 sequester ribosomal components and suppress translation
p26 condensates from Pea enation mosaic virus 2 sequester ribosomal components and suppress translation
PRJNA1151067 | ENA
ProteomicsLost in translation? Proteomic evidence for a muted molecular response to thermal stress in a stenothermal Antarctic fish and possible evolutionary mechanisms
Antarctic notothenioid fishes are noteworthy for their history of isolation and indications they lack the heat shock response. The mechanistic basis for stenothermy has not been fully elucidated, and some aspects of stenothermy could arise post-transcriptionally. Antarctic emerald rockcod (Trematomu...
ORGANISM(S): Trematomus Bernacchii 
PXD051983 | panorama
TranscriptomicsTranslation profiling of Drosophila during early embryogenesis
Translational control is critical for early Drosophila embryogenesis and is exerted mainly at the gene-specific level. To understand the post-transcriptional regulation during Drosophila early embryonic development, we used the sucrose polysomal gradient analyses and GeneChip analysis to illustrate ...
ORGANISM(S): Drosophila melanogaster 
2008-03-14 | E-GEOD-5430 | biostudies-arrayexpress
TranscriptomicsExamination of gene expression in cerebellum and hippocampus for mouse C57BL/6J WT and nmf205-/-
Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathways we analyzed the brain of B6J-nmf205-/- mice in which neuronal elongation complexes are stall...
ORGANISM(S): Mus musculus 
2016-06-15 | E-GEOD-79926 | biostudies-arrayexpress
UnknownFGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.
Not available
S-EPMC6072612 | biostudies-literature
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