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Polycistronic mRNAs transcribed from operons are resolved via the trans-splicing of a spliced leader (SL) RNA. The SL is also frequently trans-spliced to monocistronic transcripts. Using a modified cap analysis of gene expression (CAGE) protocol we mapped sites of SL trans-splicing genome-wide in th...
ORGANISM(S): Oikopleura dioica 
Meiotic maturation of vertebrate oocytes occurs in the near-absence of transcription. Thus, female fertility relies on timely translational activation of maternal transcripts stockpiled in full-grown prophase-I-arrested oocytes. However, how expression of these mRNAs is suppressed to maintain the lo...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2025-07-18 | PXD062261 | Pride
Singlet oxygen induced RNA oxidation and translational arrest
DNA damage caused by UV radiation initiates cellular recovery mechanisms, which involve activation of DNA damage response pathways, cell cycle arrest and apoptosis. To assess cellular transcriptional responses to UVC-induced DNA damage we compared time course responses of human skin fibroblasts to l...
ORGANISM(S): Homo sapiens 
Crosstalk between eIF2α and eEF2 phosphorylation pathways optimizes translational arrest in response to oxidative stress
Singlet oxygen induced RNA oxidation and translational arrest [DCMU]
Singlet oxygen induced RNA oxidation and translational arrest [RB]
Singlet oxygen induced RNA oxidation and translational arrest [CHX]
Co-translational targeting defect caused by Srp68 knockout leads tomeiotic arrest during spermatogenesis in mice
Singlet oxygen induced RNA oxidation and translational arrest [flu mutant]
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