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ProteomicsMultiple C2 domains and Transmembrane region Proteins (MCTPs) tether membranes at plasmodesmata
In eukaryotes, membrane contact sites (MCS) allow direct communication between organelles. Plants have evolved unique MCS, the plasmodesmata intercellular pores, which combine organelle tethering with regulation of cell-to-cell signalling, the molecular mechanisms of which remains unknown. Here,...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-07-08 | PXD013999 | Pride
Plasmodesmata Lc-ms 
GenomicsDifferential requirement for the Ire1 luminal and transmembrane domains in Candida albicans drug resistance and pathogenicity
Differential requirement for the Ire1 luminal and transmembrane domains in Candida albicans drug resistance and pathogenicity
PRJNA1481423 | ENA
GenomicsHigh-throughput pyrosequencing of forum domains termini (FT) isolated and amplified from human HEK293T cells
Forum domains are stretches of chromosomal DNA that are excised from eukaryotic chromosomes during their spontaneous non-random fragmentation. Mostly forum domains are of 50-200 kb in length, although larger domains, up to 500 - 700 kb, are also observed. We performed a genome-wide mapping of forum ...
ORGANISM(S): Homo sapiens 
2013-03-31 | E-GEOD-35065 | biostudies-arrayexpress
TranscriptomicsTiling path analysis of Drosophila Schneider 2 cultured cells to map forum domains
Forum domains are stretches of chromosomal DNA that are excised from eukaryotic chromosomes during their spontaneous non-random fragmentation. Mostly forum domains are of 50-200 kb in length, although larger domains, up to 500 - 700 kb, are also observed.

We performed a genome-wide mapping o...
ORGANISM(S): Drosophila melanogaster 
2010-11-01 | E-MEXP-2468 | biostudies-arrayexpress
UnknownIsolated Toll-like receptor transmembrane domains are capable of oligomerization.
Not available
S-EPMC3498381 | biostudies-literature
ProteomicsTop-down proteomics of membrane proteoforms from HeLa cells and mouse hippocampus
Comprehensive characterization of membrane proteins at the level of proteoforms in complex biological samples by top-down mass spectrometry is of vital importance in revealing their precise functions. Based on a novel membrane protein separation technology, we obtained a dataset of membrane proteofo...
ORGANISM(S): Homo Sapiens Mus Musculus 
2023-02-08 | PXD039949 |
ProteomicsProteomics of extracellular vesicles from Fusarium oxysporum
Through proteomic analysis using mass spectrometry, a total of 1,931 proteins enriched in Fo-EVs were identified. Among these proteins, 350 were found to contain signal peptides and 375 possessed transmembrane domains. GO annotation and enrichment analysis, using the whole-genome proteins as backgro...
ORGANISM(S): Fusarium oxysporum f. sp. lycopersici 4286 
2026-01-05 | PXD071461 | Pride
Fusarium oxysporum ，extracellular vesicles，proteomics 
TranscriptomicsDifferential requirement for the Ire1 luminal and transmembrane domains in Candida albicans drug resistance and pathogenicity
The opportunistic human pathogen Candida albicans depends on the unfolded protein response (UPR) for cell wall integrity, antifungal tolerance, filamentous growth, and virulence. The UPR is driven by the conserved transmembrane sensor Ire1, which is activated either by misfolded proteins through its...
ORGANISM(S): Candida albicans 
2026-09-22 | GSE336334 | GEO
UnknownLocalized lipid packing of transmembrane domains impedes integrin clustering.
Not available
S-EPMC3597534 | biostudies-literature
UnknownFusion with wild-type SNARE domains is controlled by juxtamembrane domains, transmembrane anchors, and Sec17.
Not available
S-EPMC9282010 | biostudies-literature
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