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UV crosslinking can be used to identify precise RNA targets for individual proteins, transcriptome-wide. We sought to develop a technique to generate reciprocal data, identifying precise sites of RNA-binding proteome-wide. The resulting technique, total RNA-associated protein purification (TRAPP), r...
ORGANISM(S): Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2019-03-26 | PXD011071 | Pride
Defining the RNA Interactome by Total RNA-Associated Protein Purification
UV crosslinking can be used to identify precise RNA targets for individual proteins, transcriptome-wide. We sought to develop a technique to generate reciprocal data, identifying precise sites of RNA-binding proteome-wide. The resulting technique, total RNA-associated protein purification (TRAPP), w...
ORGANISM(S): Saccharomyces cerevisiae 
2018-09-13 | GSE119867 | GEO
Mutations in the human RMRP gene cause Cartilage Hair Hypoplasia (CHH), an autosomal recessive disorder characterized by skeletal abnormalities and impaired T-cell activation. RMRP encodes a non-coding RNA, which forms the core of the RNase MRP ribonucleoprotein complex. In budding yeast, RMRP cleav...
ORGANISM(S): Homo sapiens (Human) 
2021-03-30 | PXD025029 | Pride
The type 6 secretion system immunity protein RhsFI has been repurposed for small RNA regulation in pathogenic E. coli
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