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TranscriptomicsFunctions of the Mediator subunit Med31 in Candida albicans support a role in shaping species-specific gene expression.
Mediator is an essential, evolutionarily conserved co-regulator of RNA polymerase II. Studies in model yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe showed remarkably conserved roles for Mediator despite high species divergence, and thus whether Mediator contributed to establishment ...
ORGANISM(S): Candida albicans 
2012-02-20 | E-GEOD-31632 | biostudies-arrayexpress
TranscriptomicsCell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2
The cell wall is essential for viability of fungi and is an effective drug target in pathogens such as Candida albicans. The contribution of posttranscriptional gene regulators to cell wall integrity in C. albicans is unknown. We show that the C. albicans Ccr4-Pop2 mRNA deadenylase, a regulator of m...
ORGANISM(S): Candida albicans 
2010-12-10 | E-GEOD-25891 | biostudies-arrayexpress
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