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Mycobacterium tuberculosis is a global killer causing over a million deaths from tuberculosis (TB) every year. It is therefore a major burden on human health. To reduce the deadly impact of TB, we need a better understanding of the strategies used by M. tuberculosis to adapt its...

2026-08-07 | MTBLS13438 | MetaboLights

Telenomus remus, an egg parasitoid capable of penetrating multi-layered egg masses, has emerged as a promising candidate for the biological control of Spodoptera frugiperda. Nevertheless, our prior investigations have uncovered that its limited cold tolerance represents a critical bottleneck in m...

2025-06-09 | MTBLS12473 | MetaboLights

INTRODUCTION: The production of high quality and safe food represents a main priority for the agri-food sector in the effort to sustain the exponentially growing human population. Nonetheless, there are major challenges that require the discovery of new, alternative, and improved...

2020-09-08 | MTBLS1565 | MetaboLights
Voit2003 - Trehalose Cycle This model is described in the article: Biochemical and genomic regulation of the trehalose cycle in yeast: review of observations and canonical model analysis. Voit EO. J. Theor. Biol. 2003 Jul; 223(1): 55-78 Abstract: The physiological...
2024-09-02 | BIOMD0000000266 | BioModels
Effect of the TPS1 transgene on the transcriptome in potato
ORGANISM(S): Solanum tuberosum 
To understand the organisation of the glucose regulatory system, we analysed 91 deletion mutants of established glucose signalling and metabolic pathway members in Saccharomyces cerevisiae by DNA microarrays. These deletion mutants do not induce pathway-specific transcriptional responses reflecting ...
ORGANISM(S): Saccharomyces cerevisiae 
ApoE-knockout mice liver on high fat diet developing liver steatosis were treated with trehalose or agmatine for 16 weeks.
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD049421 | Pride
The consequences of trehalose intake on brain metabolism in mice
Effect of mycobacterial cell wall component TDM (trehalose dimycolate) of murine macrophage gene expression.
ORGANISM(S): Mus musculus 
Highly concentrated trehalose induces prohealing senescence-like state in fibroblasts via CDKN1A/p21
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