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TranscriptomicsTranscription profiling of human glucose-dependent insulinotropic peptide (GIP)- and adrenocorticotropin-dependent adrenal hyperplasias reveals novel targets for the study of GIP-dependent Cushings syndrome.
The mechanisms responsible for the ectopic adrenal expression of glucose-dependent insulinotropic peptide (GIP) receptor (GIPR) in GIP-dependent Cushing's syndrome (CS) are unknown. Chronic adrenal stimulation by ACTH in Cushing's disease or GIP in GIP-dependent ACTH-independent macronodular adrenal...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-4060 | biostudies-arrayexpress
TranscriptomicsFanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1
Fanconi anemia (FA) is a genetic disorder characterized by congenital abnormalities, bone marrow failure and increased susceptibility to cancer. Of the fifteen FA proteins, Fanconi anemia group C (FANCC) is one of eight FA core complex components of the FA pathway. Unlike other FA core complex prote...
ORGANISM(S): Homo sapiens 
2013-04-05 | E-GEOD-43330 | biostudies-arrayexpress
TranscriptomicsSCL and LMO1 reprogram thymocytes into self-renewing cells.
The SCL and LMO1 oncogenic transcription factors reprogram thymocytes into self-renewing pre-leukemic stem cells (pre-LSCs). Here we report that SCL directly interacts with LMO1 to activate the transcription of a self-renewal program coordinated by LYL1. Gene expression profiles of thymocytes from S...
ORGANISM(S): Mus musculus 
2015-11-05 | E-GEOD-74659 | biostudies-arrayexpress
TranscriptomicsA Chondrogenic Molecule that Repairs Cartilage by Transcriptional Regulation of CBF-beta
Osteoarthritis (OA) is a degenerative joint disease that involves destruction of articular cartilage and eventually leads to disability. Mesenchymal stem cells (MSCs) reside in healthy and diseased cartilage, and through their chondrogenic potential may provide a strategy for cartilage repair. To th...
ORGANISM(S): Homo sapiens 
2012-05-01 | E-GEOD-35546 | biostudies-arrayexpress
TranscriptomicsOuter cell surface components essential for Fe(III) oxide reduction in Geobacter metallireducens
The ability of Geobacter species to readily donate electrons to extracellular electron acceptors makes the study of their physiology not only important for the understanding of environmental processes, but also for industrial applications such as bioelectronics and electrosynthesis. Studies in G. su...
ORGANISM(S): Geobacter metallireducens GS-15 
2013-02-18 | E-GEOD-40316 | biostudies-arrayexpress
UnknownIdentification of genetic subtypes in follicular lymphoma.
Not available
S-EPMC11306633 | biostudies-literature
UnknownMultiple and specific mRNA processing targets for the major human hnRNP proteins.
Not available
S-EPMC2547008 | biostudies-literature
UnknownA cost efficient spatially balanced hierarchical sampling design for monitoring boreal birds incorporating access costs and habitat stratification.
Not available
S-EPMC7297386 | biostudies-literature
UnknownNogo receptor-Fc delivered by haematopoietic cells enhances neurorepair in a multiple sclerosis model.
Not available
S-EPMC10116608 | biostudies-literature
UnknownTargeting LMO2-induced autocrine FLT3 signaling to overcome chemoresistance in early T-cell precursor acute lymphoblastic leukemia.
Not available
S-EPMC11879882 | biostudies-literature
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