Triacsin c - OmicsDI

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Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation (Shotgun lipidomics assays after inhibition with FSG67 and Triacsin C)

During megakaryopoiesis, megakaryocytes (MK) undergo cellular morphological changes with strong modification of membrane composition and lipid signaling. Here we adopt a lipid-centric multi-omics approach to create a quantitative map of the MK lipidome during maturation and proplatelet formation....

2023-07-26 | MTBLS6083 | MetaboLights

Human intestinal acyl-CoA synthetase 5 is sensitive to the inhibitor triacsin C.

Not available

S-EPMC3235631 | biostudies-literature

Novel triacsin C analogs as potential antivirals against rotavirus infections.

Not available

S-EPMC3312795 | biostudies-literature

Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus.

Not available

S-EPMC4118089 | biostudies-literature

Hrd1 interaction proteomics - Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation

Endoplasmic reticulum (ER)-associated degradation (ERAD) mediates the degradation of misfolded and unoligomerized proteins in the early secretory pathway. ERAD substrates are detected and delivered to membrane-embedded dislocation complexes. Following transfer into the cytosol, substrates are rapidl...

ORGANISM(S): Homo sapiens (Human)

2017-01-03 | PXD005633 | Pride