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MetabolomicsDIATAGeR: Triacylglycerol Annotation of Data-Independent Acquisition based Lipidomics

Triacylglycerols (TGs) are the most abundant lipids in the human body and the primary source of energy storage. Altered TGs are implicated in metabolic syndrome and detailed structural information may provide novel insights into diseases pathology. TGs are comprised of three fatty acyls with vari...

2025-03-04 | MTBLS11927 | MetaboLights
MetabolomicsAnalysis of age-dependent changes of triacylglycerol species in C. elegans depleted of tif-IA and ncl-1
Not available
ORGANISM(S): Caenorhabditis elegans 
ST002326 | MetabolomicsWorkbench
TranscriptomicsPolyunsaturated fatty acids acutely affect triacylglycerol-derived skeletal muscle fatty acid uptake and increases postprandial insulin sensitivity
Dietary fat quality may influence skeletal muscle lipid handling and fat accumulation, thereby modulating insulin sensitivity. Objective: To examine acute effects of meals with various fatty acid (FA) compositions on skeletal muscle FA handling and postprandial insulin sensitivity in obese insulin r...
ORGANISM(S): Homo sapiens 
2012-02-21 | E-GEOD-31901 | biostudies-arrayexpress
ProteomicsAlgal Protein Kinase, Triacylglycerol Accumulation Regulator1, Modulates Cell Viability and Gametogenesis in Carbon/Nitrogen Imbalanced Conditions
Nutrient-deprived microalgae accumulate triacylglycerol (TAG) in lipid droplets. A Dual-specificity tyrosine phosphorylation-regulated kinase, TAG-accumulation-regulator-1 (TAR1) has been shown to be required for acetate-dependent TAG accumulation and degradation of chlorophyll and photosynthesis-re...
ORGANISM(S): Chlamydomonas 
2019-07-22 | PXD012391 | JPOST Repository
TranscriptomicsThree acyltransferases and a nitrogen responsive regulator are implicated in nitrogen starvation-induced triacylglycerol accumulation in Chlamydomonas
Three acyltransferases, DGAT1, DGTT1, and PDAT1, are induced by nitrogen starvation and are likely to have a role in TAG accumulation based on their patterns of expression. Each gene also shows increased mRNA abundance in other TAG-accumulating conditions (-S, -P, -Zn, -Fe). Insertional mutants, pda...
ORGANISM(S): Chlamydomonas reinhardtii 
2013-01-10 | E-GEOD-34585 | biostudies-arrayexpress
ProteomicsPhosphoproteomics of Chlamydomonas reinhardtii in photoautotrophic nitrogen-deficient conditions
Nutrient-deprived microalgae accumulate triacylglycerol (TAG) in lipid droplets. A dual-specificity tyrosine phosphorylation-regulated kinase, TAG accumulation regulator 1 (TAR1) has been shown to be required for acetate-dependent TAG accumulation and the degradation of chlorophyll and photosynthesi...
ORGANISM(S): Cellular Organisms 
2019-01-14 | PXD012311 | JPOST Repository
GenomicsTriacylglycerol synthesis enhances macrophage inflammatory function
Triacylglycerol synthesis enhances macrophage inflammatory function
PRJNA607504 | ENA
TranscriptomicsTranscriptomic comparison of fructose and lipid grown cultures of Ralstonia eutropha H16
Whole genome gene expression analysis was examined with Ralstonia eutropha strain H16 cultures grown in PHB production medium (recipe per Peoples and Sinskey, 1989) containing fructose or trioleate as the main carbon source. The goal of this analysis was to determine the identity of the triacylglyc...
ORGANISM(S): Cupriavidus necator 
2010-08-26 | E-GEOD-21145 | biostudies-arrayexpress
TranscriptomicsIsocaloric intake of diets differing in macronutrient content (high protein or high fat) in adult rats indicate adverse effects as analysed by hepatic transcriptomics
Intake of high-protein (HP) diets has increased over the last years, mainly due to their popularity for body weight control. Liver is the main organ handling ingested macronutrients and it is associated with the beginning of different pathologies. We aimed to deepen our knowledge on molecular pathwa...
ORGANISM(S): Rattus norvegicus 
2017-05-02 | E-GEOD-57858 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Chlamydomonas reinhardtii response to nitrogen deprivation
Chlamydomonas reinhardtii forms lipid droplets rich in triacylglycerols when nutrient-deprived. To begin studying the mechanisms underlying this process, N-deprivation was used to induce triacylglycerol accumulation and changes in developmental programs such as gametogenesis. Comparative global anal...
ORGANISM(S): Chlamydomonas reinhardtii 
2010-09-24 | E-GEOD-24365 | biostudies-arrayexpress
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