Sort   by:  
 Page size 
TranscriptomicsGene expression profiling of the effect of elevated TRIB3 expression on the transcriptional response to glucose deprivation
Gene expression profiling of HEK293-derived cell lines that are stably transfected with either a tetracycline-inducible TRIB3 expression construct (TRIB3-293 cells), tetracycline-inducible ATF4 expression construct (ATF4-293 cells) or the corresponding empty vector (Vector-293 cells). Samples from t...
ORGANISM(S): Homo sapiens 
2016-02-09 | E-MTAB-3318 | biostudies-arrayexpress
ProteomicsTrib3 modulates PPAR-mediated growth inhibition by interfering with the MLL complex in breast cancer cells
Dysregulation of pathways due to mutations on oncogenes or tumor suppressors that leads to aberrant expression or activity of proteins is the most well understood mechanism that drives cancer initiation and progression. TRIB3, a member of the Tribbles family of pseudokinases, is often found dysregul...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD036341 | Pride
Mll complex Breast cancer cells Trib3 Ppar 
ProteomicsThe pseudokinase TRIB3 controls adipocyte lipid homeostasis and proliferation in vitro and in vivo
Objective: In vivo studies in humans and mice have implicated the pseudokinase Tribbles 3 (TRIB3) in various aspects of energy metabolism. Whilst cell-based studies indicate a role for TRIB3 in adipocyte differentiation and function, it is unclear if and how these cellular functions may contribute t...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-26 | PXD046703 | Pride
Tribbles  adipocyte  omics analyses  metabolism 
GenomicsThe effect of TRIB3 overexpression on mouse hepatocytes
The effect of TRIB3 overexpression on mouse hepatocytes
PRJNA974003 | ENA
GenomicsmRNA expression of Control or TRIB3-silenced MCF7 cells
mRNA expression of Control or TRIB3-silenced MCF7 cells
PRJNA479849 | ENA
ProteomicsComprehensive Profiling of Mammalian Tribbles Interactomes Implicates TRIB3 in Gene Repression
The three human Tribbles (TRIB) pseudokinases have been implicated in a plethora of signaling and metabolic processes linked to cancer initiation and progression and can potentially be used as biomarkers of disease and prognosis. While their modes of action reported so far center around protein–prot...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD030404 | Pride
Tribbles  proteomics  interactome  breast cancer 
GenomicsParishin B Blocking TRIB3-AKT1 interaction inhibits Breast cancer Lung Metastasis
Parishin B Blocking TRIB3-AKT1 interaction inhibits Breast cancer Lung Metastasis
PRJNA1203633 | ENA
GenomicsEffect of TRIB3 overexpressing on the gene expression in NCM460 cells
Effect of TRIB3 overexpressing on the gene expression in NCM460 cells
PRJNA1157806 | ENA
GenomicsChIP-Seq of TRIB3 and ATF4 in HepG2 cells treated with bortezomib
ChIP-Seq of TRIB3 and ATF4 in HepG2 cells treated with bortezomib
PRJNA702470 | ENA
GenomicsExpression data from Control or TRIB3-silenced HCT-8 cells
Expression data from Control or TRIB3-silenced HCT-8 cells
PRJNA418984 | ENA
Sort   by:  
 Page size