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MetabolomicsMetabolomics reveals increased toxicity in earthworms (Eisenia fetida) of the transformation product methyl-triclosan
The effects of the antimicrobial triclosan (TCS) and its transformation product methyl-triclosan (MTCS) on the earthworm Eisenia fetida were investigated using GC-MS metabolomics. TCS is ubiquitous in sewage sludge, but a large proportion is transformed into MTCS during wastewater treatment and in s...
2018-09-17 | MTBLS532 | MetaboLights
TranscriptomicsToxicogenomic response of Rhodospirillum rubrum S1H to the model micropollutant triclosan
Aiming at the development of a micropollutant biosensor in the frame of the Micro-Ecological Life Support System Alternative (MELiSSA), a pilot study was initiated to identify triclosan (TCS)-responsive biomarker genes in the MELiSSA carbon-mineralizing microorganism, Rhodospirillum rubrum S1H. TCS ...
ORGANISM(S): Rhodospirillum rubrum 
2010-05-19 | E-GEOD-16189 | biostudies-arrayexpress
TranscriptomicsThe transcriptomic response of E. coli to triclosan exposure
The gene expression profile of E. coli K-12 MG1655 grown in minimal medium treated with 0.12 mg/L of the biocide triclosan has been analysed using whole genome oligonucleotide microarrays. "Control" RNA was isolated from three independently grown 50ml MOPS minimal media cultures of E. coli K-12 MG16...
ORGANISM(S): Escherichia coli 
2010-10-08 | E-GEOD-15059 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica serovar Typhimurium exposure to triclosan
S. Typhimurium SL1344 was exposed to the minimum inhibitory concentration of triclosan and the transcriptomic response analysed.
ORGANISM(S): Salmonella enterica 
2009-08-28 | E-MEXP-2078 | biostudies-arrayexpress
TranscriptomicsS_aureus_&_triclosan
A triclosan-ciprofloxacin cross-resistant mutant strain of Staphylococcus aureus displays an alteration in the expression of several cell membrane structural and functional genes. Triclosan is an antimicrobial agent found in many consumer products. Several studies have demonstrated that triclosan ...
ORGANISM(S): Staphylococcus aureus 
2010-05-26 | E-GEOD-5799 | biostudies-arrayexpress
ProteomicsEffects of Triclosan and its alternatives on LPS-stimulated THP-1 macrophages
In this study, the effects of Triclosan (TCS) and its alternatives, including Benzalkonium chloride (BAM), Benzethonium chloride (BEC), Chloroxylenol (CEO), Chlorhexidine (CHX) and Cetylpyridinium chloride (CPC), were investigated in THP-1 macrophages. For this purpose, untargeted proteomics was app...
ORGANISM(S): Homo sapiens (Human) 
2024-02-05 | PXD044828 | Pride
Thp-1 Bam Ceo Cpc Tcs Chx Proteome Bec Lc-ms/ms 
GenomicsTriclosan TraDIS sequencing
Triclosan TraDIS sequencing
PRJEB29311 | ENA
TranscriptomicsComparison of gene expression in S.aureus strains with different triclosan sensitivities
Difference in sensitivity for the biocide triclosan has been observed in S.aureus. This may rely on changes in gene expression between strains. The present project investigates such changes in in vivo generated mutants and in clinical isolates.
ORGANISM(S): staphylococcus aureus 
2015-04-30 | E-MTAB-2127 | biostudies-arrayexpress
TranscriptomicsMicroarray Analysis of Toxicogenomic Effects of Triclosan on Mycobacterium bovis BCG
Global gene expression analysis of Mycobacterium bovis BCG following Triclosan treatment using Affymetrix GeneChip arrays. Results from this study provide insight into the molecular mechanisms underlying the cellular response of Mycobacterium bovis BCG to Triclosan We conducted three independent mic...
ORGANISM(S): Mycobacterium bovis BCG 
2012-12-25 | E-GEOD-33800 | biostudies-arrayexpress
Genomicstriclosan-sludge
The effect of triclosan on activated sludge
PRJEB1049 | ENA
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